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. 2024 Nov 14;22(11):e9016. doi: 10.2903/j.efsa.2024.9016

TABLE 4.

Flavouring compounds already assessed by EFSA as chemically defined flavourings, grouped according to the chemical group (CG) as defined in Commission Regulation (EC) No 1565/2000, with indication of the EU Flavour Information System (FLAVIS) number and the corresponding EFSA opinion.

CG Chemical group Product (EU register name) FLAVIS No. EFSA* opinion, year
01 Straight‐chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes Hexan‐1‐ol 02.005 2013
03 a, ß‐Unsaturated (alkene or alkyne) straight‐chain and branched‐chain aliphatic primary alcohols/aldehydes/acids, acetals and esters Geraniol 02.012 2016a
(Z)‐Nerol 02.058
trans‐3,7‐Dimethylocta‐2,6‐dienal (geranial) 05.188
Geranyl acetate 09.011
Geranyl formate 09.076
Neryl formate 09.212
Neryl acetate 09.213
Hex‐2(trans)‐enal 05.073 2019b
04 Non‐conjugated and accumulated unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids, acetals and esters Hex‐3(cis)‐en‐1‐ol 02.056 2016b
05 Saturated and unsaturated aliphatic secondary alcohols, ketones and esters with esters containing secondary alcohols 6‐Methylhept‐5‐en‐2‐one 07.015 2015a
06 Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols and esters with esters containing tertiary alcohols ethers Linalool 02.013 2012a, 2020
α‐Terpineol 02.014 2012a
2‐(4‐Methylphenyl)propan‐2‐ol 02.042
4‐Terpinenol 02.072
Linalyl acetate 09.013
Linalyl formate 09.080
Sclareol 1 02.206 2011a, CEF
08 Secondary alicyclic saturated and unsaturated alcohols, ketones, ketals and esters with ketals containing alicyclic alcohols or ketones and esters containing secondary alicyclic alcohols d,l‐Borneol 02.016 2016c
d,l‐Bornyl acetate 09.017
10 Secondary aliphatic saturated or unsaturated alcohols, ketones, ketals and esters with a second secondary or tertiary oxygenated functional group 4‐Hydroxy‐4‐methylpentan‐2‐one 1 07.165 2008, AFC
13 Furanones and tetrahydrofurfuryl derivatives Linalool oxide 2 13.140 2012b
15 Phenyl ethyl alcohols, phenylacetic acids, related esters, phenoxyacetic acids and related esters Phenylacetaldehyde 05.030 2012c
16 Aliphatic and alicyclic ethers 1,8‐Cineole 03.001 2012d, 2021
3,6‐Dihydro‐4‐methyl‐2‐(2‐methylprop‐1‐en‐1‐yl)‐2H‐pyran 1 13.088 2011b, CEF
23 Benzyl alcohols, aldehydes, acids, esters and acetals Benzaldehyde 05.013 2012e
Methyl salycilate 09.749
31 Aliphatic and aromatic hydrocarbons and acetals containing saturated aldehydes 1‐Isopropyl‐4‐methylbenzene (p‐cymene) 01.002 2015b
Terpinolene 01.005
α‐Terpinene 01.019
γ‐Terpinene 01.020
d‐Limonene 01.045
Pin‐2(10)‐ene (β‐pinene) 01.003 2016d
Pin‐2(3)‐ene (α‐pinene) 01.004
β‐Caryophyllene 01.007
Myrcene 01.008
Camphene 01.009
β‐Cubebene 1 , 3 01.030 2011c, CEF

Germacra‐1(10),4(14),5‐triene

δ‐Germacrene 1 , 3

01.042
3,7,10‐Humulatriene 1 , 3 01.043
4(10)‐Thujene (sabinene) 1 01.059 2015a, CEF

cis‐3,7‐Dimethyl‐1,3,6‐octatriene

(Z)‐β‐Ocimene 1

01.064
β‐Bourbonene 1 01.024
α‐Farnesene 1 01.040
32 Epoxides β‐Caryophyllene epoxide 1 16.043 2014, CEF
*

FEEDAP opinion unless otherwise indicated.

1

Evaluated for use in food. According to Regulation (EC) 1565/2000, flavourings evaluated by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) before 2000 are not required to be re‐evaluated by EFSA.

2

Linalool oxide [13.140]: A mixture of cis‐ and trans‐linalool oxide (5‐ring) was evaluated [13.140] (EFSA FEEDAP Panel, 2012b).

3

Evaluated applying the ‘Procedure’ described in the Guidance on the data required for the risk assessment of flavourings to be used in or on food (EFSA CEF Panel, 2010). No longer authorised for use as flavours in food.