TABLE 2.
Experimental animals’ body weight, liver weight, and weight gain.
| Parameters | Experimental group | |||||
|---|---|---|---|---|---|---|
| Normal control group (DW; 10 mL/kg) | Toxic control group (DW; 10 mL/kg) | Standard group (Silymarin; 100 mg/kg) | J. regia extract (500 mg/kg) | J. regia extract (250 mg/kg) | J. regia extract (125 mg/kg) | |
| Initial body weight (g) | 276.50 ± 22.39 | 241.84 ± 13.80 | 231.84 ± 6.64 | 285.67 ± 28.65 | 260.50 ± 21.39 | 258.34 ± 19.74 |
| Final body weight (g) | 300.16 ± 22.38 | 260.67 ± 17.11 | 250.16 ± 10.31 | 290.84 ± 29.27 | 265.67 ± 23.87 | 270.50 ± 19.87 |
| Weight gain (g) | 23.67 ± 1.20 | 18.84 ± 2.54 | 18.84 ± 4.10 | 5.16 ± 1.97a–c | 5.16 ± 3.26a–c | 12.16 ± 3.74 |
| Liver weight (g) | 10.62 ± 1.12 | 11.40 ± 0.78 | 10.84 ± 0.93 | 12.79 ± 1.36 | 10.20 ± 1.33 | 11.51 ± 1.52 |
| Relative liver weight | 3.49 ± 0.14 | 4.44 ± 0.38 | 4.31 ± 0.25 | 4.55 ± 0.64 | 3.79 ± 0.23 | 4.18 ± 0.38 |
Note: The results depict the average and standard error of mean (SEM) of six rats. Administered vehicle: DW (distilled water), olive oil, and CCl4 in 1:1 ratio at a dose of 1.5 mL/kg was administered via i.p. route on eighth day with all groups, except the normal control group. Relative liver weight = (Liver weight/Body weight) × 100. a–c p < .05 significantly different from the normal, toxic, and standard control group, respectively.