Table 2.
Overview of Likely Transmission Events.
| Patient | Pathogen | Year | Culture-positive burn patient | Comparator | |||
|---|---|---|---|---|---|---|---|
| Specimen source | Susceptibility profile | Specimen source(s) | Susceptibility profile | Patient type | |||
| 1 | Acinetobacter baumannii complex | 2020 | Tissue culture | Sensitive to: Ceftazidime Tobramycin TMP-SMX Meropenem Resistant to: Cefazolin Ciprofloxacin Indeterminate to: Ceftriaxone Pip-Tazo |
Blood | Sensitive to: Ceftazidime Gentamicin Tobramycin TMP-SMX Ceftriaxone Pip-Tazo Meropenem Resistant to: Cefazolin Ciprofloxacin |
Burn |
| 2 | Pseudomonas aeruginosa | 2020 | Wound swab/tissue culture | Sensitive to: Ceftazidime Gentamicin Tobramycin Pip-Tazo Resistant to: Meropenem Indeterminate to: Ciprofloxacin |
Wound swab/tissueculture/ urine |
Sensitive to: Ceftazidime Gentamicin Tobramycin Pip-Tazo Resistant to: Meropenem Indeterminate to: Ciprofloxacin |
Burn |
| 3 | Acinetobacter baumannii complex | 2020 | Tissue culture | Sensitive to: Ceftazidime Gentamicin Tobramycin TMP-SMX Ceftriaxone Pip-Tazo Meropenem Resistant to: Cefazolin Indeterminate to: Ciprofloxacin |
Blood | Sensitive to: Ceftazidime Tobramycin TMP-SMX Ceftriaxone Pip-Tazo Meropenem Resistant to: Cefazolin Indeterminate to: Ciprofloxacin Gentamicin |
Burn |
| Wound swab | Sensitive to: Ciprofloxacin Gentamicin Tobramycin TMP-SMX Pip-Tazo Meropenem Resistant to: Cefazolin Indeterminate to: Ceftazidime |
Nonburn | |||||
| 4 | P. aeruginosa | 2020 | Wound swab/ tissue culture |
Sensitive to: Ceftazidime Gentamicin Tobramycin Pip-Tazo Resistant to: Meropenem Indeterminate to: Ciprofloxacin |
Wound swab/ tissue culture |
Sensitive to: Ceftazidime Gentamicin Tobramycin Pip-Tazo Resistant to: Meropenem Indeterminate to: Ciprofloxacin |
Burn |
| 5 | MRSA | 2019 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Wound swab (1), tissue culture (1) | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Burn & nonburn |
| 6 | MRSA | 2019 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Burn |
| 7 | MRSA | 2019 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Wound swab (1), wound swab/tissue culture (1), blood (1) | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Burn & nonburn |
| 8 | MRSA | 2018-2019 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Wound swab (3), wound swab/tissue culture (1), blood (2) | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Burn & nonburn |
| 9 | MRSA | 2018 | Wound swab/ tissue culture |
Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Wound swab (4), blood (2) | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Burn & nonburn |
| 10 | MRSA | 2018 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Wound swab/tissue culture | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Burn |
| Blood | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin Penicillin |
Nonburn | |||||
| 11 | MRSA | 2018 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin Penicillin |
Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline TMP-SMX Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin |
Nonburn |
| 12 | Coagulase-negative Staphylococci | 2017 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin Penicillin TMP-SMX |
Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin TMP-SMX |
Burn |
| 13 | Coagulase-negative Staphylococci | 2017 | Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin TMP-SMX |
Wound swab | Sensitive to: Clindamycin Gentamicin Nitrofurantoin Rifampin Tetracycline Vancomycin Resistant to: Cefazolin Ciprofloxacin Erythromycin Levofloxacin Cloxacillin Penicillin TMP-SMX |
Burn |
| 14 | Streptococcus mitis | 2017 | Tissue culture | Sensitive to: Vancomycin Ceftriaxone Indeterminate to: Penicillin |
Blood | Sensitive to: Vancomycin Ceftriaxone Indeterminate to: Penicillin |
Burn |
| 15 | Serratia marcescens | 2016-2017 | Tissue culture | Sensitive to: Amikacin Ciprofloxacin Ceftazidime Gentamicin Tobramycin TMP-SMX Ceftriaxone Ertapenem Meropenem Resistant to: Ampicillin Cefazolin Nitrofurantoin |
Wound swab/ tissue culture |
Sensitive to: Amikacin Ciprofloxacin Cefixime Ceftazidime Gentamicin Ceftriaxone Ertapenem Meropenem Resistant to: Ampicillin Cefazolin Nitrofurantoin |
Nonburn |
| Vancomycin-resistant Enterococcus faecium | Wound swab/ tissue culture |
Sensitive to: Gentamicin Nitrofurantoin Resistant to: Ciprofloxacin Levofloxacin Penicillin Tetracycline Vancomycin Ampicillin |
Tissue culture/stool | Resistant to: Ciprofloxacin Levofloxacin Gentamicin Penicillin Vancomycin Ampicillin Indeterminate to: Nitrofurantoin |
Nonburn | ||
| 16 | Coagulase-negative Staphylococci | 2016 | Wound swab/ tissue culture |
Sensitive to: Nitrofurantoin Rifampin Vancomycin Resistant to: Cefazolin Ciprofloxacin Clindamycin Erythromycin Levofloxacin Gentamicin Imipenem Cloxacillin Penicillin Tetracycline TMP-SMX |
Wound swab/ tissue culture/blood |
Sensitive to: Nitrofurantoin Rifampin Vancomycin Resistant to: Cefazolin Ciprofloxacin Clindamycin Erythromycin Levofloxacin Gentamicin Imipenem Cloxacillin Penicillin Tetracycline TMP-SMX Clarithromycin Ceftriaxone Cefurox |
Burn |
| 17 | Coagulase-negative Staphylococci | 2015-2016 | Wound swab/ tissue culture |
Sensitive to: Nitrofurantoin Rifampin Vancomycin Resistant to: Cefazolin Ciprofloxacin Clindamycin Erythromycin Levofloxacin Gentamicin Imipenem Cloxacillin Penicillin Tetracycline TMP-SMX Clarithromycin Ceftriaxone Cefurox |
Wound swab/ tissue culture/blood |
Sensitive to: Nitrofurantoin Rifampin Vancomycin Resistant to: Cefazolin Ciprofloxacin Clindamycin Erythromycin Levofloxacin Gentamicin Imipenem Cloxacillin Penicillin Tetracycline TMP-SMX |
Burn |
| 18 | Staphylococcus aureus | 2012 | Wound swab | Sensitive to: Cefazolin Ciprofloxacin Levofloxacin Gentamicin Imipenem Nitrofurantoin Cloxacillin Rifampin Tetracycline TMP-SMX Vancomycin Ceftriaxone Cefurox Resistant to: Clindamycin Erythromycin Penicillin Clarithromycin |
Wound swab | Sensitive to: Cefazolin Ciprofloxacin Levofloxacin Gentamicin Imipenem Nitrofurantoin Cloxacillin Rifampin Tetracycline TMP-SMX Vancomycin Ceftriaxone Cefurox Resistant to: Clindamycin Erythromycin Penicillin Clarithromycin |
Nonburn |
Abbreviations: MRSA, methicillin-resistant Staphylococcus aureus; Pip-Tazo,Piperacillin-Tazobactam; TMP-SMX, Trimethoprim-Sulfamethoxazole.