Table 1.
Family history of patients/families in the three experiments: GWAS, direct sequencing, and Maldi-tof + association study
| 1. GWAS; 685 cases (510 sporadic) | 2. SEQ; 122 cases (all familial) | 3. Association; 827 cases (all familial) | Sub cohort; 293 cases (all familial) | |
|---|---|---|---|---|
| Number of cancer cases among relatives to the index patients in the different experiments | ||||
| Breast | 276 | 52 | 262 | 110 |
| Pancreatic | 36 | 8 | 49 | 18 |
| Gastric | 523 | 123 | 216 | 211 |
| Prostate | 468 | 96 | 201 | 193 |
| Gynaecologic | 143 | 27 | 161 | 58 |
| Biliary tract | 21 | 3 | 15 | 9 |
| Lung | 106 | 14 | 112 | 44 |
| Bladder | 28 | 3 | 38 | 13 |
| Leukaemia/lymphoma | 91 | 25 | 120 | 49 |
| Skin/melanoma | 61 | 19 | 58 | 34 |
| CNS | 59 | 11 | 72 | 26 |
| Renal | 35 | 4 | 36 | 14 |
| Other | 395 | 70 | 459 | 179 |