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. 2024 Nov 13;22:531. doi: 10.1186/s12916-024-03759-4

Table 2.

Results of the semiquantitative expression analysis of relevant epithelial cell markers in control human native corneas (CTR-C), control human native scleral limbi (CTR-L), and human artificial corneas (HAC) using immunohistochemistry and immunofluorescence. PCK, human cytokeratin cocktail pancytokeratin; AE1/AE3, human cytokeratin cocktail AE1/AE3; KRT5, cytokeratin 5; CRYλ, crystallin λ; CRYαa, crystallin alpha a; CX43, connexin 43; TJP1, tight junction protein 1; KRT3, cytokeratin 3; KRT19, cytokeratin 19; KRT15, cytokeratin 15; ΔNp63, limbal isoform of the protein p63. The staining signal was assessed as negative ( −), slightly positive (+ / −), positive ( +), very positive (+ +), or strongly positive (+ + +)

CTR-C CTR-L HAC
PCK  + +   + +   + + + 
AE1/AE3  + + +   + + +   + + + 
KTR5  + + +   + + +   + + 
CRYλ  + + +   + + +   + + 
CRYαa  + + +   + +   + + + 
CX43  + +   + +   + + 
TJP1  + +   + +   + + 
KRT3  + + +   +   + / − 
KRT19  +   + +   + + 
KRT15 -  + +   + + 
ΔNp63  +   + +   + +