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Table 4.

Correlation analyses for TNFRs in patients with DM.

Log TNFR1 Log TNFR2
T1DM (n = 76) T2DM (n = 575) T1DM (n = 76) T2DM (n = 575)
r P r P r P r P
Age 0.172 0.138 0.280 <0.001 0.196 0.090 0.326 <0.001
BMI 0.289 0.012 0.025 0.550 0.260 0.024 −0.002 0.968
Systolic BP 0.395 <0.001 0.134 0.001 0.315 0.006 0.126 0.025
Diastolic BP 0.037 0.748 −0.128 0.002 0.018 0.876 −0.125 0.003
Heart rate −0.030 0.796 −0.001 0.866 0.040 0.732 −0.043 0.308
Log (duration of DM) 0.302 0.008 0.238 <0.001 0.264 0.023 0.244 <0.001
Total protein −0.178 <0.001 0.103 0.374 −0.165 <0.001 0.102 0.381
Log AST 0.339 0.003 0.900 0.005 0.340 0.003 0.079 0.058
Log ALT 0.268 0.020 −0.105 0.012 0.235 0.041 −0.062 0.134
Log γGTP 0.449 <0.001 0.040 0.344 0.421 <0.001 0.071 0.088
BUN 0.716 <0.001 0.661 <0.001 0.691 <0.001 0.613 <0.001
Log creatinine 0.852 <0.001 0.747 <0.001 0.776 <0.001 0.709 <0.001
eGFR −0.762 <0.001 −0.655 <0.001 −0.713 <0.001 −0.641 <0.001
Uric acid 0.321 0.004 0.328 <0.001 0.320 0.005 0.328 <0.001
TC −0.167 0.149 −0.250 <0.001 −0.246 0.036 −0.287 0.089
LDL-C −0.120 0.301 −0.245 <0.001 −0.158 0.174 −0.279 <0.001
HDL-C −0.235 0.041 −0.268 <0.001 −0.312 0.006 −0.268 <0.001
Non-HDL-C −0.042 0.716 −0.157 <0.001 −0.084 0.470 −0.196 <0.001
Log triglycerides 0.228 0.048 0.102 0.015 0.191 0.098 0.078 0.062
Log CRP 0.486 <0.001 0.254 <0.001 0.471 <0.001 0.253 <0.001
Log glucose 0.014 0.908 0.012 0.769 0.028 0.809 0.001 0.992
Log (hemoglobin A1c) −0.029 0.807 −0.034 0.420 −0.001 0.996 −0.056 0.180
Log C-peptide 0.385 <0.001 0.096 0.022 0.283 0.013 0.070 0.093
Log TNFR1 0.956 <0.001 0.940 <0.001
Log TNFR2 0.956 <0.001 0.940 <0.001
Log FABP4 0.546 <0.001 0.366 <0.001 0.519 <0.001 0.334 <0.001

ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; BP, blood pressure; BUN, blood urea nitrogen; CRP, C-reactive protein; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; FABP4, fatty acid-binding protein 4; γGTP, γ-glutamyl transpeptidase; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; T1DM, type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus; TNFR, tumor necrosis factor receptor.