Figure 5. MiR-642a-3p knockdown suppressed growth of orthotopic liver tumors.

(A) Nude mice and liver tissues in the NC and shmiR-642a-3p groups. Four animals were shown in each group (n = 5). (B) Growth curve of the nude mice. (C) The structures of the liver tissues were observed by HE staining (n = 3). Magnification: 2× and 10×. (D) Ki67 expressions were analyzed using immunohistochemistry (n = 3). Magnification: 10×. (E) Expression levels of miR-642a-3p and SERPINE1 gene were detected by RT-qPCR (n = 3). (F) Protein expression was analyzed using western blot (n = 5). *P < 0.05, **P < 0.01, and ***P < 0.001.