Table 2. Results of univariate and multivariate analysis.
APACHE Ⅱ, Acute Physiology and Chronic Health Evaluation Ⅱ; CCI, Charlson Comorbidity Index; SOFA, Sequential Organ Failure Assessment; CKRT, Continuous Kidney Replacement Therapy; PMX-DHP, direct hemoperfusion using polymyxin B-immobilized fiber column; IABP, Intra-Aortic Balloon Pumping; Impella®️, percutaneous ventricular assist device; SBP, Systolic Blood Pressure; DBP, diastolic blood pressure; HR, heart rate; BT, body temperature; RR, respiratory rate; SpO2, saturation of percutaneous oxygen; GCS, Glasgow Coma Scale; P/F, partial pressure of arterial oxygen/fraction of inspiratory oxygen; PaCO2, partial pressure of arterial carbon dioxide; HFNC, high-flow nasal cannula
| Variables | Unadjusted | Adjusted | ||
| Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | |
| Age | 1.006 (0.994-1.022) | 0.326 | ||
| Sex | 1.301 (0.997-1.947) | 0.202 | ||
| CCI | 1.019 (0.948-1.095) | 0.617 | ||
| APACHE Ⅱ | 1.050 (1.019-1.081) | 0.001 | ||
| SOFA | 1.124 (1.063-1.188) | <0.001 | 1.078 (1.015-1.145) | 0.014 |
| Sepsis | 1.530 (0.975-2.401) | 0.064 | ||
| ICU LOS | 1.019 (0.952-1.090) | 0.410 | ||
| MV | 1.164 (0.789-1.718) | 0.443 | ||
| MV days | 1.053 (1.017-1.091) | 0.980 | ||
| Tracheotomy | 1.342 (0.780-2.311) | 0.288 | ||
| PMX-DHP | 1.855 (0.925-3.722) | 0.082 | ||
| CKRT | 2.305 (1.512-3.515) | <0.001 | 1.769 (1.122-2.790) | 0.014 |
| ECMO | 0.629 (0.083-4.759) | 0.654 | ||
| IABP | 0 (0-0) | 0.998 | ||
| Impella®︎ | 1.906 (0.227-15.97) | 0.552 | ||
| SBP | 1.004 (0.995-1.014) | 0.360 | ||
| DBP | 1.002 (0.998-1.016) | 0.768 | ||
| HR | 1.020 (1.010-1.031) | <0.001 | ||
| BT | 1.422 (1.091-1.855) | 0.009 | ||
| RR | 1.094 (1.057-1.132) | <0.001 | 1.072 (1.034-1.122) | <0.001 |
| SpO2 | 0.915 (0.842-0.995) | 0.037 | 0.922 (0.854-1.005) | 0.066 |
| GCS | 0.877 (0.817-0.941) | <0.001 | 0.863 (0.794-0.938) | <0.001 |
| P/F | 0.998 (0.996-0.999) | 0.006 | ||
| PaCO2 | 1.000 (0.999-1.002) | 0.684 | ||
| pH | 11.68 (0.403-338.4) | 0.154 | ||
| Sleep disorder | 9.954 (6.587-15.04) | <0.001 | 9.742 (6.315-15.02) | <0.001 |
| Delirium | 1.417 (0.734-2.735) | 0.298 | ||
| Tracheal suctioning | 2.659 (1.695-4.171) | <0.001 | 2.053 (1.288-3.273) | 0.002 |
| Catecholamine | 1.249 (0.486-3.209) | 0.644 | ||
| Cold extremities | 1.094 (0.518-2.310) | 0.814 | ||
| Low-flow oxygen therapy | 0.764 (0.513-1.136) | 0.184 | ||
| HFNC | 0.846 (0.361-1.985) | 0.701 | ||