FIGURE 3.
Relationships between CLDN18.2 expression and genomic alterations across ten cancers. Correlations of TMB (A) and MSI (B) with CLDN18.2 expression across ten cancers. Differences in levels of methylation (C) and CNV (D) between high- and low-CLDN18.2 expression groups. Mutation profiles between the high- (E) and low-CLDN18.2 (F) expression groups in STAD. Protein mutation lollipop plots for TP53 (G) and ARID1A (H) between high- and low-CLDN18.2 expression groups in STAD. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001; ns, not statistically significant.