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. 2024 Nov 1;15:1454713. doi: 10.3389/fphar.2024.1454713

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Copyright © 2024 Lu, Xiong, Zhang, Wang, Feng, Pu, Wei, Chen, Chen and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of D-mannose on inflammatory factors and oxidative stress. Western blotting analysis of the secretion of inflammation-related proteins: (A) iNOS; (B) COX-2; ELISA analysis of inflammatory cytokines; (C) IL-10; (D) IL-6; (E) IL-1β; (F) TNF-α; Oxidative stress index analysis; (G) GSH; (H) MDA; (I) SOD. Data were expressed as mean ± SD. **p < 0.01 compared with sham group. ***p < 0.001 compared with sham group; ****p < 0.0001 compared with sham group; #p < 0.05 compared with TNBS model control group. ##p < 0.01 compared with TNBS model control group. ###p < 0.001 compared with TNBS model control group. n = 10 mice.