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. 2024 Nov 1;11:1468886. doi: 10.3389/fnut.2024.1468886

Table 2.

Influence of Holder pasteurization on the growth factor composition of human milk.

Growth factor Effect Reference
TGF- β1 (99, 126)
TGF- β2 (65, 99)
EGF (99, 126, 127)
HGF (49)
IGF-1 (39%) (127)
IGF-2 (10%) (127)
IGFBP-2 (19%) (127)
IGFBP-3 (7%) (127)
GM-CSF (65)

(↓) A significant reduction in growth factor level occurred.

(–) No significant effect on growth factor concentration was observed.(↑) A significant increase in growth factor occurred.