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. 2024 Sep 3;30(11):3106–3113. doi: 10.1038/s41591-024-03245-7

Extended Data Fig. 3. Associations between mean temperature and perinatal mortality by number of knots and their location.

Extended Data Fig. 3

Sensitivity analysis: The figure depicts the pooled estimates evaluating heat effect by applying a varying number of knots and adjusting their locations (1 knot at the 50th and 75th, 2 knots at the 25th and 50th, 2 knots at the 50th and 75th, 2 knots at the 50th and 90th, 2 knots at the 75th and 90th, 3 knots at the 10th, 50th, and 90th, and 3 knots at the 25th, 50th, and 75th). Our main model included 3 knots at the 10th, 75th and 90th percentile. The estimates are presented as odds ratio (OR) and 95% confidence intervals obtained from conditional logistic regression models. The estimates show the association of an increase in temperature (from the 75th to the 99th percentile) the week before birth (lag 0–6) on stillbirths, antepartum stillbirths, intrapartum stillbirths, and perinatal deaths.