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. 2024 Aug 29;4(11):1544–1561. doi: 10.1038/s43587-024-00695-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — Immunohistochemistry analysis of immune cell markers in young (90 days) S6K1 WT and KO mice. a. Haematoxylin and eosin (H/E) staining, MHCII staining for antigen-presenting cells, CD68 staining for monocytes and macrophages, CD3 staining for T cells and B220 staining for B cells in liver sections. Scale bar, 100 μm. b. Heatmap depicting the expression of key chemokines, cytokines and proteases in young S6K1 WT (90 days; n = 5) and young S6K1 KO (90 days; n = 5) mice. WT, wild-type. KO, knockout. Data are representative of a single experiment.