Table 5.

Comparison of our study with published models for binary classification of Alzheimer’s disease vs. healthy control (HC)

Paper	Dataset	Method	Validation	Results (%)
Cassani and Falk (2019)	20 HC, 34 AD	Spectral feature extraction, ANOVA, SVM	LOSO CV	Acc: 88.1, F1 86.2
Vecchio et al. (2020)	120 HC, 175 AD	Exact low-resolution brain electromagnetic tomography, SVM	Hold-out CV (80:20)	Acc: 95.0, Sen: 95.0, Spe: 96.0
Alves et al. (2022)	24 HC, 24 AD	Pearson’s correlation, custom-designed CNN, hyperparameter optimization	tenfold CV	Acc: 100, Pre: 100, Rec: 100
Dogan et al. (2022)	11 HC, 12 AD	Primate brain pattern, INCA, kNN	tenfold CV	Acc: 100, Pre: 100, Rec: 100
Our model	8 HC, 1 AD	Lattice123, MDWT, INCA, kNN, IHMV, greedy algorithm	tenfold CV	Experiment 1: • Acc:98.37, GM:96.74
				Experiment 2: • Acc:99.62, GM:99.45
				Experiment 3: • Acc:98.74, GM:97.52
	Alternative dataset 11 HC, 12 AD			Acc: 100, Pre: 100, Rec: 100