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. 2024 Oct 18;10(21):e39547. doi: 10.1016/j.heliyon.2024.e39547

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© 2024 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 3 — Distinct microbial compositions between tumour and non-tumour tissues of HB. (A) Differences in taxa between the tumour and non-tumour regions of HB determined via the LefSe analysis. (B) Boxplot analysis of the relative abundance of the top nine different genera between the tumour and non-tumour groups. (C) Random forest point map of the top 30 different bacteria genera. (D) Heatmap of the different Kyoto Encyclopaedia of Genes and Genomes pathways for the tumour and non-tumour groups. (E) Heatmap of the association analysis between the differential microbiome and clinical indicators. The red points represent positive correlation, and the bluerepresent negative correlation; ∗ represents P < 0.05; ∗∗ represents P < 0.01.