Table 5.
Independent Predictors of Moderate to Severe Atrophic Gastritis and Intestinal Metaplasia of the Corpus at Logistic Regression Analysis
| Variable | No. of subjects (%) or mean±SD |
HR | 95% CI | p-value |
|---|---|---|---|---|
| Atrophic gastritis | ||||
| Male | ||||
| Age, yr | 59.67±8.87 | 1.038 | 0.990–1.088 | 0.126 |
| Drinking (no vs yes) | 8 (27.6) vs 13 (10.0) | 0.221 | 0.073–0.666 | 0.007 |
| IL-1B-511 (CT+TT vs CC) | 14 (10.4) vs 7 (26.9) | 4.377 | 1.387–13.814 | 0.012 |
| oipA (negative vs positive) | 15 (19.0) vs 6 (7.2) | 0.349 | 0.123–0.991 | 0.048 |
| Female | ||||
| Age, yr | 60.19±7.98 | 1.061 | 1.014–1.110 | 0.010 |
| IL-8-251 (AT+TT vs AA) | 15 (6.0) vs 9 (21.4) | 3.799 | 1.515–9.523 | 0.004 |
| IL-8-781 (CC+CT vs TT) | 18 (7.0) vs 6 (19.4) | 1.182 | 0.316–4.426 | 0.804 |
| Intestinal metaplasia | ||||
| Male | ||||
| Age, yr | 60.73±10.77 | 1.064 | 1.017–1.113 | 0.007 |
| IL-8-251 (AT+AA vs TT) | 7 (5.6) vs 13 (13.4) | 3.128 | 1.149–8.512 | 0.026 |
| IL-10-592 (AA vs CA+CC) | 6 (5.1) vs 14 (12.7) | 2.334 | 0.837–6.503 | 0.105 |
| Female | ||||
| Age, yr | 53.36±10.23 | 1.048 | 1.008–1.090 | 0.019 |
HR, hazard ratio; CI, confidence interval.