Table 1. Characteristics of COPD patients with sepsis.
| Variables | Total (n=2,964) | Aspirin non-users (n=1,322) | Aspirin users (n=1,642) | P value |
|---|---|---|---|---|
| Age (years) | 65 [57, 72] | 62 [52, 71] | 67 [60, 73] | <0.001 |
| Gender | ||||
| Male | 1,590 (53.644) | 651 (49.244) | 939 (57.186) | <0.001 |
| Female | 1,374 (46.356) | 671 (50.756) | 703 (42.814) | |
| BMI (kg/m2) | 28.742 [24.200, 34.100] | 28.400 [23.700, 34.300] | 28.900 [24.447, 33.900] | 0.28 |
| Heart rate (bmp) | 71 [62, 82] | 75 [63, 87] | 69 [61, 79] | <0.001 |
| SBP (mmHg) | 86 [78, 95] | 87 [78, 97] | 86 [78, 95] | 0.19 |
| DBP (mmHg) | 44 [39, 50] | 45 [39, 52] | 44 [39, 49] | <0.001 |
| SpO2 (%) | 92 [89, 94] | 91 [89, 94] | 92 [90, 94] | <0.001 |
| With renal disease | 559 (18.860) | 197 (14.902) | 362 (22.046) | <0.001 |
| With coronary artery disease | 951 (32.085) | 129 (9.758) | 822 (50.061) | <0.001 |
| With diabetes | 1,008 (34.008) | 351 (26.551) | 657 (40.012) | <0.001 |
| With hypertension | 1,120 (37.787) | 322 (24.357) | 798 (48.599) | <0.001 |
| Vasopressor use | 1,228 (41.430) | 546 (41.301) | 682 (41.535) | 0.90 |
| Mechanical ventilation use | 550 (18.556) | 298 (22.542) | 252 (15.347) | <0.001 |
| With CRRT | 215 (7.254) | 124 (9.380) | 91 (5.542) | <0.001 |
| GCS | 15 [15, 15] | 15 [15, 15] | 15 [15, 15] | 0.06 |
| SOFA | 3 [2, 4] | 3 [2, 5] | 3 [2, 4] | 0.85 |
| Glucose (mg/dL) | 101 [86, 125] | 108 [89, 131] | 96 [84, 118] | <0.001 |
| Hematocrit (%) | 24.0 [21.0, 28.5] | 24.6 [21.0, 29.1] | 24.0 [21.0, 28.0] | 0.01 |
| Platelets (mL) | 161 [113, 231] | 169 [106, 247] | 158 [116, 220] | 0.21 |
| WBC (K/μL) | 10.3 [7.3, 13.7] | 10.1 [7.0, 14.0] | 10.3 [7.6, 13.4] | 0.36 |
| Pt (sec) | 13.3 [12.0, 15.2] | 13.5 [12.1, 16.0] | 13.2 [12.0, 14.7] | <0.001 |
| Urine output (mL) | 15 [5, 30] | 15 [3, 30] | 15 [5, 29] | 0.78 |
Categorical variables were expressed by count (frequency), and continuous variables were represented by the median [interquartile range]. COPD, chronic obstructive pulmonary disease; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; SpO2, oxygen saturation; CRRT, continuous renal replacement therapy; GCS, Glasgow Coma Scale; SOFA, Sequential Organ Failure Assessment; WBC, white blood cell; Pt, prothrombin time.