Anti-inflammatory activity of aurasperone B and ergosterol.
Treatments | Conc. (mg kg−1) | Percentage inhibition after different time intervalsa | ||||
---|---|---|---|---|---|---|
1 h | 2 h | 3 h | 4 h | 5 h | ||
Aspirin | 10 | 68.48 ± 1.87 | 78.8 ± 0.76 | 89.67 ± 1.51 | 95.11 ± 1.43 | 98.91 ± 1.21 |
Aurasperone B | 5 | 60 ± 1.23 | 63.64 ± 1.21 | 66.67 ± 0.98 | 77.58 ± 1.23 | 77.58 ± 0.44 |
10 | 61.11 ± 1.25 | 66.67 ± 1.126 | 72.84 ± 0.76 | 79.01 ± 1.01 | 79.01 ± 0.32 | |
15 | 66.87 ± 1.98 | 72.29 ± 1.56 | 78.92 ± 0.43 | 84.94 ± 1.04 | 84.94 ± 0.12 | |
Ergosterol | 10 | 54.04 ± 2.12 | 59.01 ± 1.43 | 66.46 ± 1.46 | 74.53 ± 1.21 | 74.53 ± 0.98 |
20 | 54.09 ± 2.18 | 59.75 ± 1.72 | 67.92 ± 1.22 | 74.84 ± 1.04 | 74.84 ± 1.34 | |
30 | 58.9 ± 2.45 | 65.64 ± 1.42 | 72.39 ± 1.08 | 79.75 ± 0.56 | 79.75 ± 1.33 |
Data shown is processed through one-way ANOVA, followed by Dunnett's test.