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. 2024 Nov 15;14(49):36527–36537. doi: 10.1039/d4ra03674c

Anti-inflammatory activity of aurasperone B and ergosterol.

Treatments Conc. (mg kg−1) Percentage inhibition after different time intervalsa
1 h 2 h 3 h 4 h 5 h
Aspirin 10 68.48 ± 1.87 78.8 ± 0.76 89.67 ± 1.51 95.11 ± 1.43 98.91 ± 1.21
Aurasperone B 5 60 ± 1.23 63.64 ± 1.21 66.67 ± 0.98 77.58 ± 1.23 77.58 ± 0.44
10 61.11 ± 1.25 66.67 ± 1.126 72.84 ± 0.76 79.01 ± 1.01 79.01 ± 0.32
15 66.87 ± 1.98 72.29 ± 1.56 78.92 ± 0.43 84.94 ± 1.04 84.94 ± 0.12
Ergosterol 10 54.04 ± 2.12 59.01 ± 1.43 66.46 ± 1.46 74.53 ± 1.21 74.53 ± 0.98
20 54.09 ± 2.18 59.75 ± 1.72 67.92 ± 1.22 74.84 ± 1.04 74.84 ± 1.34
30 58.9 ± 2.45 65.64 ± 1.42 72.39 ± 1.08 79.75 ± 0.56 79.75 ± 1.33
a

Data shown is processed through one-way ANOVA, followed by Dunnett's test.