Figure 13.
Representative examples that show in vitro model of AS
(A) The micro-engineered arterial wall device on a chip and the migration of SMCs under hyperlipidemic conditions (scale bar 500 μm). Copyright 2021, Royal Society of Chemistry, Reproduced with permission.229
(B) Bright-field views of TEBVs, along with macrophage polarization within these vessels following exposure to eLDL and/or TNF-α (scale bar i: 200 μm, ii: 100 μm). Copyright 2020, Springer Nature, Reproduced with permission.105
(C) The structure of the early-stage AS model and the actual model, as well as the morphology of HUVECs under different mechanical stimuli (scale bar 50 μm). Copyright 2016, Wiley-VCH, Reproduced with permission.230
(D) The schematic diagram illustrates the fabrication process of triple-layered AEs, resulting in arterial constructs with controlled geometries. Copyright 2021, Wiley-VCH, Reproduced with permission.231
(E) The schematic view depicts the assembly of ps-plaques with blood-derived cells and reveals the inner architecture of these ps-plaques (scale bar 100 μm). Copyright 2018, Elsevier Science, Reproduced with permission.232