Representative AEs constructed by in vivo bioengineered
(A) Implanting transparent nylon molds subcutaneously in beagle dogs, tubular collagenous tissue is formed, which, after decellularization to acquire a biotube and allogeneic transplantation, successfully facilitates arterial reconstruction three months post-procedure. Copyright 2018, Elsevier, Reproduced with permission.169
(B) The integration of polymer melt spinning technology with in vivo engineering has enhanced the mechanical properties of hMPBs, ensuring their maintenance of original shape and structure post-surgical manipulations (scale bar 100 μm). Copyright 2022, American Association for the Advancement of Science, Reproduced with permission.170