Table 1. Popular Radiometals for (Pre)Clinical Applications2,3.
| radionuclide | half-life (h) | decay modea | applicationa |
|---|---|---|---|
| 44Sc | 4.04 | β+ (94%), EC (6%) | PET |
| 47Sc | 80.4 | β– (100%) | β– therapy, SPECT |
| 66Ga | 9.49 | β+ (57%), EC (43%) | PET |
| 67Ga | 78.2 | EC (100%) | SPECT |
| 68Ga | 1.13 | β+ (89%), EC (11%) | PET |
| 86Y | 14.7 | β+ (32%), EC (68%) | PET |
| 90Y | 64.0 | β– (100%) | β– therapy |
| 110mIn | 1.15 | β+ (61%), EC (39%) | PET |
| 111In | 67.2 | EC (100%) | SPECT |
| 114mIn | 1188 | IT (γ emission, 97%) | Auger electron therapy |
| 149Tb | 4.12 | α (17%), β+ (7%), EC (76%) | α therapy, PET |
| 152Tb | 17.5 | β+ (20%), EC (80%) | PET |
| 155Tb | 128 | EC (100%) | SPECT |
| 161Tb | 165 | β– (100%) | β– and Auger electron therapy, SPECT |
| 177Lu | 159 | β– (100%) | β– therapy, SPECT |
| 212Bi | 1.01 | α (36%), β– (64%) | α and β– therapy |
| 213Bi | 0.76 | α (2%), β– (98%) | α and β– therapy |
| 225Ac | 238 | α (100%) | α therapy |
| 99mTc | 6.02 | IT (γ emission) | SPECT |
| 89Zr | 78.4 | β+ (100%) | PET |
| 64Cu | 12.7 | β+ (19%), β– (40%), EC (41%) | β– and Auger electron therapy, PET |
a
α, α particle; β– = β particle; β+, positron; EC, electron capture; IT, isomeric transition; SPECT, single photon emission computed tomography; PET, positron emission tomography.