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. 2024 Nov 14;46(2):2427158. doi: 10.1080/0886022X.2024.2427158

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 2. — WGCNA analysis of differentially expressed genes. (A) a cluster dendrogram representing 96 kidney tissue samples, including 47 IgAN samples and 49 healthy control samples, along with the corresponding mean connectivity values at various soft threshold powers. (B) a cluster dendrogram of the genes. (C) Correlations between module eigengenes and clinical traits of IgAN. (D) a cluster dendrogram of differentially expressed genes to identify the clinically significant modules associated with IgAN. (E) Relationships between different modules and clinical traits, where red represents positive correlation and blue indicates negative correlation. (F) Correlation of module membership and gene significance within the turquoise module. Datasets from GSE93798 and GSE37460.