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. 2024 Nov 14;46(2):2427158. doi: 10.1080/0886022X.2024.2427158

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 4. — Develpment of IgAN diagnostic model using LASSO-based logistic regression analysis. (A) Construction and screening of a diagnostic model based on 5 hub genes through LASSO-based logistic regression; (B) Univariate cox analysis assessing the prognostic value of FAM genes concerning IgAN. (C) Distribution of risk scores and a heatmap illustrating the prognostic five-gene signature within the database. (D) Kaplan-Meier survival analysis comparing patients with high and low risk scores. (E) Boxplots depicting the expression of hub genes in glomerular tissue samples from IgAN and healthy control groups. Datasets from GSE93798 and GSE37460.