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. 2024 Nov 14;24:3168. doi: 10.1186/s12889-024-20700-9

Table 2.

Associations between total flavonoid intake and femur BMD in individuals ≥ 20 years

Exposure:
Total flavonoids quartiles
Model 1
β (95% CI) P value
Model 2
β (95% CI) P value
Model 3
β (95% CI) P value
Total femur BMD
 Q1 Reference Reference Reference
 Q2 0.007 (−0.002, 0.016) 0.103 0.010 (0.002, 0.017) 0.013 0.009 (0.002, 0.016) 0.004
 Q3 0.001 (−0.008, 0.010) 0.769 0.012 (0.005, 0.020) 0.001 0.010 (0.001, 0.019) < 0.011
 Q4 0.004 (−0.005, 0.013) 0.379 0.017 (0.009, 0.025) < 0.001 0.013 (0.004, 0.022) 0.001
P for trend 0.680  < 0.001 0.003
Femoral neck BMD
 Q1 Reference Reference Reference
 Q2 −0.000 (−0.009, 0.008) 0.985 0.004 (−0.003, 0.011) 0.242 0.003 (−0.002, 0.008) 0.102
 Q3 −0.009 (−0.017, −0.000) 0.047 0.006 (−0.001, 0.013) 0.08247 0.007 (0.002, 0.012) 0.044
 Q4 −0.003 (−0.011, 0.006) 0.496 0.012 (0.005, 0.019) < 0.001 0.010 (0.004, 0.017) 0.001
P for trend 0.205  < 0.001 0.006
Trochanter BMD
 Q1 Reference Reference Reference
 Q2 0.007 (−0.000, 0.014) 0.065 0.009 (0.002, 0.016) 0.008 0.006 (−0.001, 0.012) 0.086
 Q3 0.004 (−0.003, 0.012) 0.244 0.012 (0.005, 0.019) < 0.001

0.007 (0.001, 0.014)

0.034

 Q4 0.009 (0.001, 0.016) 0.024 0.016 (0.010, 0.023) < 0.001 0.010 (0.004, 0.017) 0.001
P for trend 0.054  < 0.001 0.002
Intertrochanter BMD
 Q1 Reference Reference Reference
 Q2 0.009 (−0.002, 0.019) 0.093 0.011 (0.002, 0.020) 0.019 0.008 (0.002, 0.014) 0.031
 Q3 0.002 (−0.008, 0.012) 0.702 0.014 (0.005, 0.023) 0.003 0.010 (0.001, 0.018) 0.020
 Q4 0.003 (−0.007, 0.014) 0.513 0.018 (0.009, 0.028) < 0.001 0.012 (0.003, 0.020) 0.006
P for trend 0.833  < 0.001 0.008

MEC weight was adjusted. Model 1: no covariates were adjusted. Model 2: age gender, and race/ethnicity were adjusted

Model 3: age, gender, race/ethnicity, BMI, PIR, education level, drinking behavior, smoking behavior, physical activities, total protein, serum calcium, serum uric acid, cholesterol, serum phosphorus, blood urea nitrogen, and HEI-2015

Abbreviations: BMD bone mineral density, BMI body mass index, PIR poverty and income ratio, HEI-2015 Healthy Eating Index-2015, MEC Mobile Examination Center