Table 4.

Synergistic Effects of SDT-Derived Therapies with Chemotherapy, Photothermal Therapy, and Immunotherapy

Synergistic Treatment	Mechanism of Action	Key Advantages	Unique Feature
Chemotherapy	Enhances drug delivery via sonoporation	Lowers drug dose and side effects	Overcomes drug resistance
Photothermal Therapy	Heat combined with SDT-induced ROS	Improves tumor destruction	Dual effect: Heat and ROS
Immunotherapy	Stimulates immune response with ROS	Boosts immune system activation	Supports long-term immune memory