Table 3.
Clinicopathological characteristics of patients treated with ICIs
| Characteristics | Category | Number |
|---|---|---|
| Gender | Male | 15 (62.5%) |
| Female | 9 (37.5%) | |
| Age | Median (range) | 64.5 (45–80) |
| ECOG PS at ICI initiation | 0 | 3 (12.5%) |
| 1 | 10 (41.7%) | |
| 2 | 11 (45.8%) | |
| PD-L1 expression | > 1% | 14 (58.3%) |
| < 1% | 10 (41.7%) | |
| Antibiotic use | Yes | 3 (12.5%) |
| No | 21 (87.5%) | |
| Corticosteroids use | Yes | 14 (58.3%) |
| No | 10 (41.7%) | |
| M1 phenotype of Macrophages | Median (range) | 4.29 (0.30–19.48) |
| M2 phenotype of Macrophages | Median (range) | 6.68 (1.40–18.41) |
| CEA (ng/ml) | Median (range) | 3.16 (0.27–1000.00) |
| HECTD2 | Low expression | 14 (58.3%) |
| High expression | 10 (41.7%) |