Table 3.

LME results based on ${\mathrm{T}}_{1\mathrm{\rho }}$ and ${\mathrm{T}}_2$ cartilage mean values of femur (${\mathrm{R}}_2$-${\mathrm{R}}_6$) and acetabular (${\mathrm{R}}_2$-${\mathrm{R}}_5$) cartilage subregions. Variables and cartilage regions showing significant correlations are presented in this table. BMI: body mass index, Sex: Male or Female, Acq_year: Longitudinal study time points, KL-score: Kellgren-Lawrence score.

	Subregions	Value (beta)	Std.Error	DF	t-value	p-value	Parameter
Mean${\mathbf{T}}_{\mathbf{1}\mathrm{\rho }}$Values	Femur ${\mathrm{R}}_2$	1.18	0.17	115	6.86	<0.0001	BMI
		7.17	1.86	35	3.86	0.0005	Sex
		3.46	1.22	115	2.84	0.0053	KL -score
	Femur ${\mathrm{R}}_3$	1.45	0.15	115	9.42	<0.0001	BMI
		4.03	1.69	35	2.38	0.021	Sex
		2.92	1.07	115	2.74	0.0071	Acq_year
	Femur ${\mathrm{R}}_4$	1.22	0.16	115	7.85	<0.0001	BMI
		4.25	1.76	35	2.41	0.0211	Sex
	Femur ${\mathrm{R}}_5$	1.55	0.16	115	9.42	<0.0001	BMI
	Femur ${\mathrm{R}}_6$	1.27	0.14	115	9.13	<0.0001	BMI
Mean ${\mathbf{T}}_{\mathbf{2}}$ Values	Femur ${\mathrm{R}}_2$	2.85	1.21	115	2.35	0.0204	KL-score
		1.08	0.17	115	6.41	<0.0001	BMI
		6.31	1.81	35	3.49	0.0013	Sex
		5.54	1.36	115	4.06	0.0001	Acq_year
	Femur ${\mathrm{R}}_3$	0.74	0.20	115	3.80	0.0002	BMI
		3.19	1.08	115	2.96	0.0038	Acq_year
	Femur ${\mathrm{R}}_4$	1.29	0.17	115	7.67	<0.0001	BMI
	Femur ${\mathrm{R}}_5$	1.33	0.18	115	7.23	<0.0001	BMI
	Femur ${\mathrm{R}}_6$	1.09	0.20	115	5.57	<0.0001	BMI

	LME results of acetabular (${\mathbf{R}}_{\mathbf{2}}$-${\mathbf{R}}_{\mathbf{5}}$) cartilage subregions						Parameter
	Subregions	Value (beta)	Std.Error	DF	t-value	p-value
Mean${\mathbf{T}}_{\mathbf{1}\mathrm{\rho }}$values	Acetabular ${\mathrm{R}}_2$	0.97	0.133	115	7.24	<0.0001	BMI
		4.57	1.43	35	3.19	0.0030	Sex
	Acetabular ${\mathrm{R}}_3$	1.69	0.13	115	13.40	<0.0001	BMI
	Acetabular ${\mathrm{R}}_4$	1.43	0.15	115	9.53	<0.0001	BMI
	Acetabular ${\mathrm{R}}_5$	1.46	0.15	115	9.84	<0.0001	BMI
		7.16	1.42	115	9.84	<0.0001	Acq_year
Mean${\mathbf{T}}_{\mathbf{2}}$values	Acetabular ${\mathrm{R}}_2$	0.83	0.14	115	5.92	<0.0001	BMI
		3.33	1.49	35	2.24	0.0317	Sex
		5.65	1.27	115	4.44	<0.0001	Acq_year
	Acetabular ${\mathrm{R}}_3$	1.38	0.13	115	10.37	<0.0001	BMI
		4.61	1.18	115	3.90	0.0002	Acq_year
	Acetabular ${\mathrm{R}}_4$	1.27	0.15	115	8.32	<0.0001	BMI
		3.05	1.20	115	2.55	0.0121	Acq_year
	Acetabular ${\mathrm{R}}_5$	1.37	0.15	115	9.40	<0.0001	BMI
		4.87	1.25	115	3.89	0.0002	Acq_year