Fig. 5.

TERT upstream mutations identified in ovarian clear cell carcinoma samples. A Classification and prevalence of TERT upstream mutations. B The presence 5’ UTR mutations was associated with significantly worse survival than lack of an upstream mutation or a mutation in the promoter region, as shown in both a univariate (HR = 4.49 versus wild type, p = 0.011) and a multivariable Cox proportional hazards analysis (HR = 3.86, versus wild type, p = 0.025, Supplementary Table S5). UTR, untranslated region; CDS, coding sequence