Table 2.
Reinfection rate three years after SVR12 according to different factors
| Reinfection, n (%) | Number of reinfection person-year | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n (%) | Yes1 | No | P3 | New cases (n) |
Person-year units (n) |
Incidence rate person-year2 | IRR, IC 95% |
p | ||
|
Type of housing (n = 183) |
Unstable | 21 (100.0) | 2 (9.5) | 19 (90.5) | 0.102 | 2 | 47.06 | 0.043 | 5.4 (0.9–32.4) | 0.0644 |
| Stable | 162 (100.0) | 3 (1.9) | 159 (98.1) | 3 | 381.82 | 0.008 | ||||
|
HBV-HCV coinfection (n = 186) |
Yes | 7 (100.0) | - | 7 (100.0) | 1.000 | 0 | 18.37 | - | - | - |
| No | 179 (100.0) | 5 (2.8) | 174 (97.2) | 5 | 416.8 | 0.012 | ||||
|
HIV-HCV coinfection (n = 186) |
Yes | 97 (100.0) | 2 (2.1) | 95 (97.9) | 0.671 | 2 | 234.89 | 0.009 | 0.6 (0.1–3.4) | 0.5361 |
| No | 89 (100.0) | 3 (3.4) | 86 (96.6) | 3 | 200.28 | 0.015 | ||||
|
Psychiatric illness (n = 186) |
Yes | 65 (100.0) | 2 (3.1) | 63 (96.9) | 1.000 | 2 | 132.82 | 0.015 | 1.5 (0.3–9.1) | 0.6477 |
| No | 121 (100.0) | 3 (2.5) | 118 (97.5) | 3 | 302.34 | 0.01 | ||||
|
High-risk sexual behavior at the reinfection time (n = 172) |
Yes | 12 (100.0) | - | 12 (100.0) | 1.000 | 0 | 30.56 | - | - | - |
| No | 160 (100.0) | 3 (1.9) | 157 (98.1) | 3 | 376.86 | 0.008 | ||||
|
Active drug user at the reinfection time (n = 183) |
Yes | 82 (100.0) | 4 (4.9) | 78 (95.1) | 0.175 | 4 | 191.26 | 0.021 | 5.0 (0.6–44.4) | 0.1517 |
| No | 101 (100.0) | 1 (1.0) | 100 (99.0) | 1 | 237.44 | 0.004 | ||||
| People who inject drugs4 (n = 81) | Yes | 2 (100.0) | 2 (100.0) | - | 0.001 | 2 | 5.59 | 0.358 | 65.7 (6.0–724.1) | 0.0006 |
| No | 79 (100.0) | 1 (1.3) | 78 (98.7) | 1 | 183.52 | 0.005 | ||||
|
OAT user5 (n = 181) |
Yes | 179 (100.0) | 5 (2.8) | 174 (97.2) | 1.000 | 5 | 419.58 | 0.012 | - | - |
| No | 2 (100.0%) | - | 2 (100.0) | 0 | 6.15 | - | ||||
|
Harm reduction program (n = 179) |
Yes | 83 (100.0) | 3 (3.6%) | 80 (96.4%) | 0.664 | 3 | 188.47 | 0.016 | 1.8 (0.3–11.0) | 0.5029 |
| No | 96 (100.0) | 2 (2.1) | 94 (97.9) | 2 | 231.62 | 0.009 | ||||
Note unavailable data have been excluded (type of accommodation n = 3, high-risk sexual behavior n = 13, patients with high-risk sexual behavior who suffered reinfection n = 2, people who use drugs n = 3, people who inject drugs n = 1, OAT n = 5, harm reduction program n = 7)
1Number of new reinfection episodes during follow-up
2Incidence rate person-year: # New cases of reinfection / Total person – time at risk (person-year units)
3Fisher’s exact test