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. 2024 Nov 14;46:23. doi: 10.1186/s41021-024-00316-6

Table 1.

Reported Ames test data

Chemical name Ames test result Test strains used Reference
Quinoline analogues
 Quinoline Mutagenic (+ S9) in TA100, TA98, WP2uvrA TA100, TA1535, TA98, TA1537, WP2uvrA (± S9) [9]
 Isoquinoline Non-mutagenic TA100, TA98 (± S9) [10]
 Quinoxaline Mutagenic (+ S9) in TA98 TA100, TA98, TA102 (± S9) [7]
Non-mutagenic TA100, TA1535, TA98, TA1537, TA1538a [7]
 Phthalazine Non-mutagenic TA100, TA98 (± S9) [11]
Indole analogues
 Indole Mutagenicb WP2, WP2uvrA/pKM101, WP2uvrA, TA102 (± S9) [12]
Non-mutagenic TA100 (-S9) [13]
Non-mutagenic TA100, TA98 (-S9) [14]
 Indazole Non-mutagenic TA100, TA98 (-S9) [14]
 Benzimidazole Weakly mutagenic in HisG46 and TA1530 (-S9)c HisG46, TA1530, TA1531, TA1532, HisD3052, TA1534 (-S9) [15]
Non-mutagenic TA100, TA98 (-S9) [14]
Non-mutagenic TA100, TA1535, TA98, TA1537, TA97 (± S9) [16]

athe presence or absence of S9 mix was not clearly indicated

btest strain showed mutagenic was not available

cconducted by a spot test