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. 2024 Nov 14;46:23. doi: 10.1186/s41021-024-00316-6

Table 3.

Results of Ames test and in silico analyses of quinoline analogues

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+++: "mutagenic (>1000 revertants/mg)" in Ames test

++: "mutagenic (100-1000 rev/mg)" in Ames test

+: "mutagenic (< 100 revertants/mg)" in Ames test, "positive" in CASE Ultra and "probable" in Derek Nexus

±: "inconclusive" in CASE Ultra and "equivocal" in Derek Nexus

-: "non-mutagenic" in Ames test, "negative" in CASE Ultra, "inactive" in Derek Nexus

DEREK version: Derek Nexus: 6.1.1, Nexus: 2.4.0, CASE Ultra Version: 1.8.0.5