Table 2.
Crude analysis of primary outcome and adjusted analyses of the primary and secondary outcomes in patients with Day3-triglyceride above 5.65 mmol/L or not
| Variables | Day3-TG ≤ 5.65 (n = 122) | Day3-TG > 5.65 (n = 108) | Difference or OR (95% CI) | p |
|---|---|---|---|---|
| Primary outcome | ||||
| OFFD, median (IQR), days* | 13.0 (10.0, 14.0) | 14.0 (10.0, 14.0) | 0 (0, 0) | 0.46 |
| OFFD, median (IQR), days# | 13.0 (10.0, 14.0) | 14.0 (10.0, 14.0) | 0.21 (− 0.66, 1.09) | 0.63 |
| Secondary outcomes# | ||||
| Composite outcome, n (%) | 16 (13.1) | 13 (12.0) | 1.13 (0.45, 2.85) | 0.80 |
| ICU-free day to day 14, median (IQR), days | 12.0 (7.0, 14.0) | 14.0 (9.0, 14.0) | − 0.57 (− 1.62, 0.48) | 0.29 |
| Hospital-free day to day 14, median (IQR), days | 5.0 (0, 7.1) | 5.0 (0.1, 7.0) | 0.32 (− 0.55, 1.20) | 0.47 |
| Hospital-free day to day 28, median (IQR), days | 19.0 (14.0, 21.0) | 19.0 (14.1, 21.0) | 0.50 (− 1.03, 2.02) | 0.52 |
| Hospital-free day to day 60, median (IQR), days | 51.0 (46.0, 53.0) | 51.0 (46.1, 53.0) | 1.72 (− 0.98, 4.41) | 0.21 |
| SOFA rank to day 14, median (IQR) | − 10.0 (− 26.0, 1.0) | − 5.0 (− 21.8, 2.50) | − 4.13 (− 9.82, 1.55) | 0.16 |
| ΔSOFA max to day 14, median (IQR) | 1.0 (0, 3.0) | 1.0 (0, 3.0) | − 0.24 (− 1.08, 0.60) | 0.58 |
| ΔSOFA14 to day 14, median (IQR) | − 1.0 (− 3.0, 0) | − 1.0 (− 2.0, 0) | − 0.39 (− 0.84, 0.06) | 0.088 |
| 60-day mortality, n (%) | 4 (3.3) | 5 (4.6) | 0.37 (0.05, 2.58) | 0.32 |
| 60-day IPN, n (%) | 2 (1.6) | 5 (4.6) | 0.33 (0.06, 2.01) | 0.23 |
| Blood purification requirement during index admission, n (%) | 47 (38.5) | 31 (28.7) | 1.80 (0.92, 3.51) | 0.087 |
| ICU requirement during index admission, n (%) | 62 (50.8) | 42 (38.9) | 1.99 (1.06, 3.74) | 0.032 |
| New-onset organ failure to day 14, n (%) | ||||
| Respiratory | 34 (27.9) | 28 (25.9) | 0.95 (0.51, 1.76) | 0.86 |
| Renal | 11 (9.0) | 13 (12.0) | 0.63 (0.26, 1.53) | 0.31 |
| Cardiovascular | 5 (4.1) | 9 (8.3) | 0.40 (0.13, 1.29) | 0.13 |
TG triglyceride, OFFD organ failure-free days to day 14, Composite outcome a composite of death from any cause by day 28 and the presence of at least one organ failure at day 7, ICU intensive care unit; SOFA, sequential organ failure assessment, IPN infected pancreatic necrosis
*Wilcoxon rank-sum test
#Adjusted for sex, age, BMI, APACHE II, and baseline TG level
Death from any cause by day 28 and the presence of at least one organ failure at day 7