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. 2024 Nov 15;23:255. doi: 10.1186/s12943-024-02130-8

Table 1.

Summary of the detection methods for cuproptosis

Related metabolic processes Detection Indicator
Cell morphology Plasma membrane rupture
Mitochondrial rupture
Metaboli index Cu ion accumulation
Alpha-ketoglutarate accumulation
Decreased succinic acid
Nucleic acid amplification testing ROS
Superoxide anion radical
Hydrogen peroxide
Glutathione metabolism FDX1
DLAT
LIAS
Protein detection HSP70 reduction
Increased Fe-S