TABLE 1.

Study demographics and plasma and CSF NfL levels in ND, PPD, and Controls.

	ND	PPD	Control
Parameter	N = 136	N = 77	N = 124	N
Age	60.8 (55.9;65.9)	54.8 (46.6;61.8)	63.2 (56.0;70.0)	337
Sex (female)	59 (43.4%)	39 (50.6%)	88 (71.0%)	337
Weight	75.0 (59.8;89.1)	84.0 (73.4;98.8)	76.0 (66.0;84.0)	250
	(n = 102)	(n = 58)	(n = 90)
Plasma NfL (pg/mL)	25.2 (15.8;39.6)	10.1 (7.85;12.5)	12.5 (8.70;17.8)	337
CSF NfL (pg/mL)	1048 (741;1585)	495 (386;671)	–	85
	(n = 63)	(n = 22)

Note: Data are median [interquartile range] or n (%).

Abbreviations: CSF, cerebrospinal fluid; NfL, neurofilament light chain; ND, neurodegenerative disorder; PPD, primary psychiatric disorder.