FIGURE 1.

Aβ peptide selectivity of MEDI1814. Aβ peptide competition of MEDI1814 to biotinylated Aβ_1‐42 using homogeneous time‐resolved fluorescence, with europium cryptate labelled anti‐human Fc immunoglobulin and XL665‐labelled streptavidin from CisBio. Peptide sequences and half‐maximal inhibitory concentration values are depicted. MEDI1814 has high selectivity for full length Aβ_1‐42 and Aβ_1‐43 (versus Aβ_1‐40) and high affinity for both full and N‐terminal‐only truncated forms of Aβ_1‐42. Aβ, amyloid beta.