Table 1.

Patient characteristics

		Data			Number of missing values
		With pathology (n = 5620)	Without pathology (n = 6521)	p-value	With pathology	Without pathology
Age (years)a		66.2 ± 8.0	65.3 ± 8.7	< 0.001
PSA (ng/mL)b		6.8 (5.1, 9.8)	5.8 (4.1, 8.4)	< 0.001	560 (9.9%)	732 (11.2%)
Previous prostate biopsy	Naive	2147 (37.9%)	1960 (30.1%)	< 0.001
	Benign	1272 (22.4%)	2356 (36.1%)
	Unknown	2251 (39.7%)	2205 (33.8%)
Family history of prostate cancer (+)		1723 (30.4%)	1667 (25.6%)	< 0.001
Family history of breast cancer (+)		578 (10.2%)	701 (10.7%)	0.33
Focal nodule on digital rectal exam (+)		546 (9.6%)	431 (6.6%)	< 0.001
Race	Caucasian	5208 (91.9%)	5911 (90.6%)	< 0.001
	African American	225 (4.0%)	229 (3.5%)
	Asian	93 (1.6%)	144 (2.2%)
	Others or unknown	144 (2.5%)	237 (3.6%)
Facility	I	3027 (53.4%)	3479 (53.4%)	0.68
	II	1190 (21.0%)	1405 (21.5%)
	III	1453 (25.6%)	1637 (25.1%)
PI-RADS	1–2	1041 (18.4%)	5720 (87.7%)	< 0.001
	3	933 (16.5%)	415 (6.4%)
	4	2052 (36.2%)	231 (3.5%)
	5	1644 (29.0%)	155 (2.4%)
Prostate volume (mL)b		46.8 (34.0, 66.6)	59.3 (41.0, 87.0)	< 0.001
PSAD (ng/mL²)b		0.14 (0.10, 0.22)	0.09 (0.06, 0.13)	< 0.001

Empty cells in the "Number of missing values" column represent no missing values. Unless otherwise specified, other data are the number of examinations, with percentages in parentheses. Proportions were compared using the chi-squared test

PI-RADS Prostate Imaging-Reporting and Data System, PSA prostate-specific antigen, PSAD prostate-specific antigen density

^a Data are the means, with the standard deviation in parentheses. The means were compared using the unpaired t-test

^b Data are the medians, with 1st and 3rd quartiles in parentheses. The medians were compared using the Wilcoxon rank sum test