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. 2024 Oct 17;16(10):e71671. doi: 10.7759/cureus.71671

Table 4. Adverse effects based on the type of COVID-19 vaccine administered.

Side effects Pfizer-BioNTech (n=422) AstraZeneca (n=126) Sinopharm (n=77) Total (n=625) P value
  n (%) n (%) n (%) n (%)  
Systemic side effect          
Headache 161 (38.2) 51 (40.5) 21 (27.3) 233 (37.3) 0.136
Fatigue 172 (40.8) 67 (53.2) 25 (32.5) 264 (42.3) 0.008
Fever 223 (52.8) 78 (61.9) 34 (44.2) 335 (53.6) 0.04
Chills and tremors 60 (14.2) 24 (19.0) 4 (5.2) 88 (14.1) 0.02
Joint pain 87 (20.6) 18 (14.3) 19 (24.7) 124 (19.8) 0.15
Myalgia 116 (27.5) 39 (31.0) 14 (18.2) 169 (27.1) 0.13
Diarrhoea 117 (27.7) 7 (5.6) 5 (6.5) 129 (20.6) 0.001
Nausea 31 (7.3) 21 (16.7) 7 (9.1) 59 (9.4) 0.007
Local side effect          
Local pain 239 (56.6) 52 (41.3) 33 (42.9) 324 (51.8) 0.002
Local oedema 56 (13.3) 18 (14.3) 12 (15.6) 86 (13.8) 0.84
Itching 24 (5.7) 15 (11.9) 5 (6.5) 44 (7.1) 0.056
Local redness 41 (9.7) 13 (10.3) 4 (5.2) 58 (9.3) 0.41
Local hotness 86 (20.4) 22 (17.5) 8 (10.4) 116 (18.6) 0.11
Duration of symptoms (Day + SD) 2.91+1.93 2.75+1.81 2.88+2.28   0.78