Figure 4.
Explanation of SCZ GWAS signals and prioritization of candidate genes
(A) GWAS enrichment results from LDSR.
(B) Fine-mapped colocalization results. Each point represents an eQTL pairs, the x axis represents the GWAS pip for that eSNP, and the y axis represents the eQTL pip for that eSNP. Red points represent pipGWAS∗pipeQTL> 0.1 and are labeled with the eGene.
(C and D) LocusZoom plots demonstrating the genetic colocalization evidence between SCZ GWAS signals (upper) and brain eQTLs (lower) at the VPS37B locus for (C) the EAS population and (D) the EUR population, respectively.