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. 2024 Nov 12;18:5109–5127. doi: 10.2147/DDDT.S490930

Table 2.

Inhibitory Effect of Compounds 5d, 5h and 5p Against VEGFR-2 Enzyme

Comp.* % Inhibition IC50 (μM)
0.01 μM 0.1 μM 1 μM 10 μM 100 μM
5d 25.47 38.92 60.42 83.51 90.97 0.274
5h 25.29 40.14 65.78 86.14 93.07 0.215
5p 31.44 44.39 70.49 88.29 93.52 0.117
SOR** 35.43 47.62 75.44 90.15 94.63 0.069

Note: *Symbols represent synthesized compounds.**SOR represents Sorafenib.