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. 2024 Oct 26;13:101779. doi: 10.1016/j.toxrep.2024.101779

Table 1.

Overview of the investigated nicotine pouches. Labeled information (nicotine content, warning labels and recommendations on intake, if available) as well as results of nicotine analytics were depicted and, in case of nicotine levels, compared with each other. GHS - Globally Harmonized System. GHS symbol 06: skull, GHS symbol 07: exclamation mark.

No. Pouch weight [g] Labeled nicotine Nicotine/pouch according to label [mg] Detected nicotine [g/100 g] Uncertainty
(± g/100 g)
Detected nicotine/pouch [mg] Difference between labeled and detected nicotine/pouch [mg] Relative difference labeled/detected nicotine/pouch [%] Warning for children (C) or pregnant women (P) GHS pictogram Recommended intake
1 0.49 - - 1.80 0.13 9.0 - - C 07
2 0.73 16 mg/g 11.7 1.63 0.12 11.9 −0.2 2 C 07
3 0.49 24 mg/g 11.8 2.38 0.17 11.7 0.1 1 C 07
4 0.54 22.5 mg/g 12.2 1.52 0.12 8.2 4 33 C, P 07
5 0.58 24 mg/g 13.9 1.57 0.12 9.1 4.8 35 C 07
6 0.4 1.5 % 6 1.42 0.11 5.7 0.3 5 C -
7 0.69 - - 0.46 0.04 3.2 - - C 07
8 0.57 15 mg/g 8.6 1.04 0.08 5.9 2.7 31 C, P 07
9 0.49 18 mg/g 8.8 1.34 0.1 6.6 2.2 25 C 07
10 0.52 50 mg/g 26 3.45 0.23 17.9 8.1 31 C 07
11 0.71 - - 1.46 0.11 10.4 - - C 07
12 0.55 - - 1.79 0.13 9.8 - - C 07
13 0.85 1.6 % 13.6 1.58 0.12 13.4 0.2 1 C -
14 0.83 1.2 % 10 1.16 0.09 9.6 0.4 4 C -
15 0.59 10 mg/pouch 10 1.45 0.11 8.6 1.4 14 C 07 20 min
16 0.76 - - 7.37 1.13 56 - - C, P 06
17 0.39 - - 3.32 0.51 12.9 - - C, P 06 30 min
18 0.44 16 mg/g 7 1.48 0.23 6.5 0.5 7 C, P 07 30 min
19 0.43 6 mg/g 2.58 0.52 0.08 2.2 0.38 15 C, P 07 30 min
20 0.38 - - 0.85 0.13 3.2 - - C, P 06 30 min
21 0.49 8 mg/pouch 8 1.15 0.09 5.6 2.4 30 C 07
22 0.69 - - 1.31 0.1 9.04 - - - -
23 0.65 - - 0.48 0.04 3.1 - - C 07
24 0.4 - - 1.99 0.31 7.96 - - C, P 06 30 min
25 0.74 - - 6.37 0.98 47.1 - - C, P 06
26 0.39 - - 2.14 0.33 8.3 - - C, P 06 30 min
27 0.42 - - 4.34 0.67 18.2 - - C, P 06 30 min
28 0.74 49.9 mg/g 36.9 4.12 0.63 30.5 6.4 17 C,P -
29 0.56 - - 5.17 0.78 29.0 - - C,P 06, 07
30 0.62 - - 7.86 1.21 48.7 - - C, P 07
31 0.48 - - 1.48 0.23 7.1 - - C, P 07 30 min