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. Author manuscript; available in PMC: 2026 Jan 1.
Published in final edited form as: Psychoneuroendocrinology. 2024 Oct 10;171:107215. doi: 10.1016/j.psyneuen.2024.107215

Table 3.

Insulin-Like Growth Factor Changes.

IGF-1 Pre-Exercise (ng/mL) IGF-1 Post-Exercise (ng/mL) IGF-1 Change (ng/mL)
Mean SD Mean SD Mean SD

Overall Differences MDD 209.56 52.80 220.82 53.15 11.27 12.93
Healthy Control 225.48 50.85 236.77 52.78 11.29 20.40
Aim 1 - HAM-D Total Mild 211.48 50.75 223.48 50.47 11.88 13.56
Moderate 216.55 57.39 227.23 57.62 10.69 10.45
Healthy Control 225.48 50.85 236.77 57.78 11.29 20.40
Aim 2 - Antidepressant Usage SSRI 188.28 43.57 200.14 43.26 11.86 12.53
Other 198.70 57.01 212.40 60.78 13.71 10.73
None 219.35 52.09 229.67 51.84 10.32 13.71
Aim 3- Physical Activity Inactive 206.88 55.40 213.16 53.93 6.28 11.76
Minimally Active 210.27 53.76 223.63 53.22 13.36 13.14
HEPA 208.33 49.46 219.51 54.10 11.18 12.75

Note. HAM-D categories based on the 17-item version, n=173 - see exclusionary criteria. HEPA: Health Enhancing Physical Activity. Inactive (0 – 599 MET min/wk), Minimally Active (600 – 2999 MET min/wk), HEPA (3000+ MET min/wk)