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. 2024 Nov 16;14:28267. doi: 10.1038/s41598-024-79556-z

Table 2.

Demographics and clinical characteristics.

Overall CA-CNSI HAVM p-Value
Number 27 13 14
Sex (n = female, (%)) 14 (51.9) 7 (53.8) 7 (50.0) 1.000
Age (as years, mean (SD)) 54.1 (15.6) 47.9 (16.2) 59.9 (13.1) 0.045
CCI (median [IQR]) 2 [0.5 – 4] 1 [0 – 5] 1.5 [1 – 4] 0.921
SAPS II (mean (SD)) 43.6 (15.0) 41.5 (16.4) 45.9 (13.7) 0.470
GCS at hospital admission (median [IQR]) 9 [5.5 – 13] 10 [7 – 12] 8 [4– 13.75] 0.507
GCS at NCCU admission (median [IQR]) 3 [3 – 4] 3 [3 – 4] 3 [3 – 4] 0.705
Seizures 0.822
None (n (%)) 14 (51.9) 6 (46.2) 8 (57.1)
Focal (n (%)) 6 (22.2) 3 (23.1) 3 (21.4)
Generalised (n (%)) 7 (25.9) 4 (30.8) 3 (21.4)
Status Epilepticus 0.564
None (n (%)) 22 (81.5) 10 (76.9) 12 (85.7)
Focal (n (%)) 1 (3.7) 1 (7.7) 0 (0)
Generalised (n (%)) 4 (14.8) 2 (15.4) 2 (14.3)

Data in brackets represent percentages. Data in square brackets represent IQR (interquartile ranges). CA-CNSI (community-acquired central nervous system infection); CCI (Charlson Comorbidity Index); GCS (Glasgow Coma Scale); HAVM (healthcare-associated ventriculitis and meningitis); NCCU (intensive care unit); SAPS II (Simplified Acute Physiology Score II). SD (standard deviation). Comparisons among patients with CA-CNSI and those with HAVM were performed.