Table 1.

Summarizing data regarding lesion type, histopathological diagnosis, and protein expression.

	Experimental groups	Macroscopy lesion type at the end of the experiment	Histopathological diagnosis	Mean immunoreactive score (min-max)
				p53	ROS1
12 weeks	Control	- Areas of white spot/plaque with a smooth surface = 4 - White plaques with an irregular surface = 7	- Epithelial dysplasia = 7 - In situ carcinoma = 4	8.1 (3–15)	7.1 (1–15)
	PBM 0.3 J	- Areas of white spot/plaque with a smooth surface = 1 - White plaques with an irregular surface = 10	- Epithelial dysplasia = 8 - In situ carcinoma = 3	6.5 (3–12)	8 (2–12)
	PBM 1 J	- Areas of white spot/plaque with a smooth surface = 1 - White plaques with an irregular surface = 5 - Nodular areas = 5	- Hyperplasia, acanthosis and hyperkeratosis = 2 - Epithelial dysplasia = 6 - In situ carcinoma = 3	6.6 (3–10)	8.5 (0–15)
20 weeks	Control	- White plaques with an irregular surface = 2 - Nodular areas = 7 - Ulcer = 2	- Epithelial dysplasia = 1 - In situ carcinoma = 1 - OSCC = 9	8.5 (5–15)	11.9 (6–15)
	PBM 0.3 J	- White plaques with an irregular surface = 2 - Nodular areas = 6 - Ulcer = 3	- Epithelial dysplasia = 1 - In situ carcinoma = 1 - OSCC = 9	7.8 (2–10)	11.3 (6–15)
	PBM 1 J	- White plaques with an irregular surface = 2 - Nodular areas = 5 - Ulcer = 5	- Epithelial dysplasia = 3 - In situ carcinoma = 2 - OSCC = 6	8.1 (2–12)	11.4 (8–15)

OSCC, oral squamous cell carcinoma.