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Neutrophil depletion decreases dsRNA-induced lung inflammation and injury. (A) Total lung PMNs via FACS analysis of whole-lung single-cell suspensions at 72 h. (n = 4 mice per group; *p < 0.05). (B) Total PMNs via BAL fluid cell count at 72 h (n = 4 mice per group; *p < 0.05). (C) Evans blue permeability index at 72 h (n = 6 mice per group; p < 0.05). Mice were pretreated control Ab or anti-PMN Ab at times -24, 0, 24, and 48 h following IT dsRNA treatment.
