Table 3.

Concordance of DWI-FLAIR mismatch assessment between realFLAIR and synthFLAIR.

Test set	Reader 1	Reader 2	Reader 3	Reader 4	Reader 5	After consensus
Subset A: Manufacturer 1, 1.5 T (n = 48)*	0.80	0.76	0.75	0.79	0.53	0.91 (0.79–1.00)
Subset B: Manufacturer 2, 1.5 T blow = 0 s/mm2 (n = 77)*	0.90	0.72	0.77	0.84	0.71	0.89 (0.79–0.99)
Subset C: Manufacturer 2, 1.5 T blow = 50 s/mm2 (n = 21)	0.53	0.67	0.59	0.39	0.49	0.63 (0.25–1.00)
Subset D: Manufacturer 3, 1.5 T (n = 13)*	0.71	0.37	0.52	0.37	0.59	0.47 (0.01–0.98)
Subset E: Manufacturer 1, 3 T (n = 12)	0.83	0.83	0.53	0.82	1.00	0.82 (0.5–1.00)
Subset F: Manufacturer 2, 3 T (n = 19)	0.87	0.87	0.88	1.00	0.89	0.87 (0.63–1.00)
Subset G: Manufacturer 3, 3 T (n = 17)	0.87	0.64	0.85	0.87	0.8	0.87 (0.61–1.00)
All subsets except Subset C (n = 186)*	0.85	0.72	0.75	0.82	0.71	0.87 (0.80–0.94)
All subsets (n = 207)*	0.83	0.73	0.75	0.79	0.70	0.85 (0.78–0.92)

Values are expressed as κ values with 95%CI in parentheses when applicable.

^*In subsets A, B, and D, respectively 2, 1, and 1 MRI sets were considered non-assessable and were thus excluded from analysis after consensus.