Table 3.

Association of selected biomarkers with poor outcome in univariable and multivariable logistic regression analysis in the SICFAIL cohort and in the STRAWINSKI/PREDICT pooled dataset.

Biomarker	Odds ratio* (95 % CI)	Odds ratio** (95 % CI)	Odds ratio*** (95 % CI)
Copeptin
SICFAIL	5.69 (3.10–10.42)	2.93 (1.57–5.45)	3.29 (1.75–6.18)
STRAWINSKI/PREDICT	6.44 (3.87–10.70)	2.11 (1.11–3.98)
Procalcitonin
SICFAIL	2.07 (1.18–3.64)	1.17 (0.59–2.31)	1.22 (0.60–2.45)
STRAWINSKI/PREDICT	1.11 (0.97–1.27)	0.99 (0.85–1.16)
Mid-regional pro atrial natriuretic peptide
SICFAIL	15.49 (7.05–34.02)	3.74 (1.39–10.01)	6.01 (2.46–14.67)
STRAWINSKI/PREDICT	13.98 (7.05–27.74)	1.76 (0.69–4.48)
N-Terminal B-type natriuretic peptide
SICFAIL	3.72 (2.63–5.26)	2.15 (1.43–3.24)	2.52 (1.71–3.71)
Cortisol
SICFAIL	16.60 (3.50–78.72)	4.43 (0.81–24.32)	5.74 (1.04–31.54)

Odds ratios are reported for logarithmic increases of base 10.

^*Univariable analysis. **Adjusted for age and NIHSS. ***Adjusted for ASTRAL score.