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. 2024 Nov 16;24:610. doi: 10.1186/s12905-024-03453-w

Table 1.

Characteristics of included studies

Author (year) Country Study Design Participants N Mean age Comparison EG (time, frequency, duration) CG/EG (time, frequency, duration) Outcomes
Abbas et al., 2023 [36] Egypt RCT Post-acute COVID-19 women (aged from 18 to 25 years) suffering from primary dysmenorrhea 30 24.5 ± 2.60 ME/NE

EG (n = 15):

10 reps/exercise, 30 min/session, 2 sessions/day, 3 days/week, 4 weeks

CG (n = 15): Non-exercise intervention VAS
Abdelaziz et al., 2020 [37] Egypt RCT Female participants (aged from 14–20 years) had main complaints that were pain and cramping during menstruation 60 17.645 ± 0.93 MBE/AC

EG (n = 30):

30 min/session, 3 sessions/week, 12 weeks

CG (n = 30): Active control (Kinesiotaping) VAS
Agrawal and Ahmed, 2021 [38] Maharashtra RCT Female students between the age group 16–25 years who were unmarried with regular menstrual cycle, and had moderate to severe dysmenorrhea. 60 NA SE/CE

EG-1 (n = 30):

5 reps + holding/exercise, 1 session/day, 6 sessions/week, 8 weeks.

EG-2 (n = 30):

10 reps + holding/exercise, 1 session/day, 6 days/week, 8 weeks.

NPRS
Akbaş and Erdem, 2019 [39] Turkey RCT Female participants (aged 18–25 years) with primary dysmenorrhea (at least 4 on a 10 cm VAS) 37 21.15 ± 1.51 AE/NE

EG (n = 18):

50 min/session, 3 sessions/week, 4 weeks

CG (n = 19): Non-exercise intervention VAS
Aksu and Vefikuluçay, 2024 [40] Turkey RCT Female university students (18 years, with regular menstrual periods) were diagnosed with primary dysmenorrhea 60 20.05 ± 1.20 MBE/NE

EG (n = 30):

60 min/session, 2 sessions/week, 12 weeks

CG (n = 30): Non-exercise intervention VAS
Amreen et al., 2013 [41] India Three-armed RCT Female students (aged between 19–25 years) were screened for primary dysmenorrhea 24 21.08 ± 1.282 RE/AC

EG-1 & EG-2 (n = 16):

30 contraction/set, 3 sets/session, 3–4 sessions/week, 8 weeks

CG (n = 8): Active control (10 min hot pack) VAS
Arora et al., 2014 [42] Navi Mumbai RCT Young female participants (aged from 19–24 years) with primary dysmenorrhea 60 20.565 ± 1.516 AE/NE

EG (n = 30):

50 min/session, 3–5 sessions/week, 12 weeks

CG(n = 30): Non-exercise intervention VAS
Azima et al., 2015 [43] Iran RCT Students residing in dormitories of Shiraz University, who were majoring in nonmedical fields and had primary dysmenorrhea 68 20.91 ± 1.15 CE/NE

EG (n = 34):

10 times/session, 2 sessions/day, 5 days/week, 8 weeks

CG (n = 34): Non-exercise intervention VAS
Behbahani et al., 2016 [44] Iran RCT Single female below 25 years old, having primary dysmenorrhea with pain intensity of four and above based on VAS 80 20.25 ± 1.52 CE/AC

EG (n = 40):

8 weeks

CG (n = 40): Active control (Routine

treatment for dysmenorrhea)

MPQ
Berde, S.D. et al., 2019 [45] India RCT Female college students with primary dysmenorrhea 50 NA CE/AE EG-1 (n = 25): 4 days/week, 8 weeks EG-2 (n = 25): 4 days/week, 8 weeks VAS
Boztas Elverisli et al., 2022 [46] Turkey Five-armed RCT Female participants (aged from 18 to 30 years) with positive primary dysmenorrhea diagnosis 46 20.335 ± 1.64 ME/NE

EG (n = 23):

60 min/session, 2 sessions/week, 12 weeks

CG (n = 23): Non-exercise intervention VAS
Celik and Apay, 2021 [47] Turkey RCT

Female students who experienced dysmenorrhea according

to the VAS (scored 5 points or more)

124 20.17 ± 1.41 SE/NE

EG (n = 64):

30 min/session, 3–7 times/week, 8 weeks

CG (n = 60): Non-exercise intervention VAS
Chaudhuri et al., 2013 [48] India RCT School girls with recurrent, spasmodic menstrual cramps (primary dysmenorrhea) 128 (112) 14 ME/AC

EG (n = 53):

10–15 min/session, 2 sessions/day, 7 days/week, 12 weeks

CG (n = 75): Active control

(Hot water bottle)

VAS
Elbandrawy and Elhakk, 2021 [49] Egypt Three-armed RCT Female participants (aged from 18–25 years) with primary dysmenorrhea 105 22.39 ± 1.89 AE/CE/NE

EG-1 (n = 35):

45 min/session, 3 sessions/week, 8 weeks

EG-2 (n = 35):

5 reps + holding/exercise, 45 min/session, 3 sessions/week, 8 weeks

CG (n = 35): Non-exercise intervention VAS
Fallah and Mirfeizi, 2017 [50] Iran Four-armed RCT College students aged 15–18 years with primary dysmenorrhea 42 15.61 ± 0.94 SE/NE EG (n = 22): 20 min/session, 3 sessions/week, 2 times/day, 8 weeks CG (n = 20): Non-exercise intervention VAS
Huang et al., 2022 [51] China (Taiwan) RCT Females (aged from 18–40 years old), being afflicted with primary dysmenorrhea 30 21.05 ± 2.31 AE/NE

EG (n = 15):

30–35 min/session, 2 sessions/week, 10 weeks

CG (n = 15): Non-exercise intervention VAS
Ibrahim et al., 2023 [52] Saudi Arabia RCT Females (18–23 years) with primary dysmenorrhea 33 20.93 ± 1.25 SE/NE

EG (n = 22):

10 reps + holding/exercise, 30–45 min/session, 3 sessions/week, 4 weeks

CG (n = 11): Non-exercise intervention VAS
Jaibunnisha et al., 2017 [53] India RCT Female participants with regular menstrual cycle and diagnosed with primary dysmenorrhea 67 NA SE/NE

EG (n = 33):

10 min/session, 1 session/day, 6 days/week, 8 weeks

CG (n = 34): Non-exercise intervention NPRS
Kannan et al., 2019 [54] New Zealand RCT Women (18–43 years) with primary dysmenorrhea 55 NA AE/NE

EG (n = 35):

3 times/week, 28 weeks

CG (n = 35): Non-exercise intervention VAS
Kaur et al., 2014 [55] India Three-armed RCT Girls of age 19–25 years with primary dysmenorrhea were selected from lovely professional university and government college 105 NA SE/MBE/NE

EG-1 & EG-2 (n = 70):

4 days/week twice for 10 min, 8 weeks

CG (n = 35): Non-exercise intervention NPRS
Khare and Jain, 2015 [56] India RCT Primary dysmenorrhea cases (aged 15–17 years) 30 NA ME/NE

EG (n = 15):

30 min/session, 2 sessions/day, 3 times/week, 3 weeks

CG (n = 15): Non-exercise intervention VAS
Kirca and Celik, 2023 [57] Turkey RCT Female university students in the 3rd and 4th year (aged from 18 to 24 years) with primary dysmenorrhea, and have a VAS value of 6 and over 60 20.38 ± 0.48 MBE/NE

EG (n = 30):

60 min/session, one session/week, 12 weeks

CG (n = 30): Non-exercise intervention VAS
Kirmizigil and Demiralp, 2020 [58] Turkey RCT Women diagnosed with primary dysmenorrhea between the ages of 18 and 35 28 23 ± 1.92 ME/NE

EG (n = 14):

50 min/session, 3 times/week, 8 weeks.

CG (n = 14): Non-exercise intervention VAS
M.I. Ortiz et al., 2015 [59] Mexico RCT

Sedentary female patients with primary dysmenorrhea aged from 18–22 years

(pain intensity from 4 to 10 cm based on VAS)

160 20.25 ± 1.21 ME/NE

EG (n = 83):

50 min/session, 3 sessions/week, 12 weeks

CG (n = 77): Non-exercise intervention VAS
Mintu Merin et al., 2020 [60] India RCT Female participants (aged from 18–25 years) with any primary dysmenorrhea symptoms 50 21.86 ± 0.904 AE/CE

EG-1:

4 days/week, 8 weeks

EG-2:

10s holding/exercise, 12 times/set, 3 sets/day, 3 days/week, 8 weeks

VAS
Motahari-Tabari et al., 2017 [61] Iran RCT Students living in the university dormitory who had moderate to severe primary dysmenorrhea for more than 50% of menstrual cycles lasting for at least one day and affected their daily activities 122 21.45 ± 2.00 SE/AC

EG (n = 61):

15 min/session, 3 sessions/week, 8 weeks

CG (n = 61): Active control (Mefenamic acid treatment) VAS
Ozturk et al., 2023 [62] Turkey Three-armed RCT

University female students who scored menstrual pain 6 or higher on

the VAS

43 19.84 ± 1.51 SE/NE

EG (n = 22):

3 times/day on the first 3 days of the menstrual cycle, 8 weeks (two menstrual cycles).

CG (n = 19): Non-exercise intervention VAS
Pastor, S. et al., 2023 [63] India RCT Female college students (aged 18–25 years) with primary dysmenorrhea 30 19 ± 1.5 CE/AE EG-1 (n = 15): 5–12 repetitions/position, 40 min/session, 1 session/day, 4 days/week, 8 weeks EG-2 (n = 15): 5–12 repetitions/position, 40 min/session, 1 session/day, 4 days/week, 8 weeks NPRS
Patel et al., 2015 [64] India RCT Female participants (aged from 17 to 25 years) with regular menstrual cycles and experienced moderate to severe primary dysmenorrhea. 120 21.32 SE/NE EG (n = 60): 2 times/day, 3 days/week, 8 weeks CG (n = 60): Non-exercise intervention VAS
Qaisar and Abbas, 2023 [65] Pakistan RCT Female participants (aged 20–30 years) with primary dysmenorrhea 24 27.32 ± 2.08 CE/AC

EG (n = 12):

20s holding×10 reps/position, 5-mins rest/set, 20 min/session, 3 sessions/week, 6 weeks

CG (n = 12): Active control (Abdominal strengthening exercise with TENS) NPRS
Raja Laxmi V. et al., 2016 [66] India RCT Female participants (aged from 18–25 years) with primary dysmenorrhea 60 NA SE/CE EG-1 (n = 30): 10 min/session, 2 sessions/day, 4 days/week, 7 weeks EG-2 (n = 30): 20 min/session, 2 sessions/day, 4 days/week, 12 weeks VAS
Rakhshaee, 2011 [67] Iran RCT Female students with primary dysmenorrhea, 18–22 years old 92 20.67 MBE/NE EG (n = 50): 20 min/session, at least 14 days of the menstrual cycle (luteal phase), 8 weeks CG (n = 42): Non-exercise intervention VAS
Rashid et al., 2019 [68] Iran RCT Participants’ age ranges from 18 to 24 with mild to moderate dysmenorrhea during the last three periods according to the McGill pain scale (1 < score < = 6.6) 86 18.65 ± 0.64 AE/AC

EG (n = 43):

20–47 min/session, 3 sessions/week, 8 weeks

CG (n = 43): Active control (Two physical education classes once a week) VAS
Rostami et al., 2006 [69] Iran RCT Students had regular menstruation and severe primary dysmenorrhea 142 16.56 ± 1.12 ME/NE

EG (n = 97):

20 min/session, 2 sessions/day, 8 weeks

CG (n = 45): Non-exercise intervention VAS
S Saleh et al., 2016 [70] Egypt Three-armed RCT Participants experienced moderate to severe symptoms of dysmenorrhea 126 20.72 ± 1.15 SE/CE/NE

EG-1 (n = 44):

4 stretching exercises, 10 min/time, 3 times/day, 3 days/week, 8 weeks

EG-2 (n = 44):

4 core strengthening exercises, 20 min/time, 3 times/day, 4 days/week, 8 weeks

CG (n = 38): Non-exercise intervention VAS
Sakuma et al., 2012 [71] Japan RCT Healthy females (aged 20–64 years) 98 33.61 ± 12.02 MBE/NE

EG (n = 67):

one session/day, 7 days/week, 2 weeks

CG (n = 31): Non-exercise intervention VAS
Samy et al., 2019 [72] Egypt RCT Participants diagnosed with primary dysmenorrhea 98 21.47 ± 1.47 AE/NE

EG (n = 49):

60 min/session, 2 times/week, 8 weeks

CG (n = 49): Non-exercise intervention VAS
Shah et al., 2016 [73] India RCT Students from SPB Physiotherapy College 40 NA SE/NE

EG (n = 20):

4 days/week, 8 weeks

CG (n = 20): Non-exercise intervention VAS
Shahrjerdi et al., 2019 [74] Iran RCT Non-athletic, unmarried girls, aged 18–25 years, who suffered from moderate to severe primary dysmenorrhea 34 22.07 ± 0.98 CE/NE

EG (n = 17):

10 reps/exercise, 45–60 min/session, 3 sessions/week, 8 weeks.

CG (n = 17): Non-exercise intervention NPRS
Shirvani et al., 2017 [75] Iran RCT Female students living in the dormitory with moderate to severe primary dysmenorrhea 122 21.46 ± 2.05 SE/AC

EG (n = 61):

15 min/session, 3 sessions/week, 8 weeks

CG (n = 61): Active control (250 mg ginger capsules) VAS
Song and Kim, 2023 [76] Republic of Korea RCT Young female participants (aged from 19–39 years) with primary dysmenorrhea 30 32.6 ± 4.18 MBE/NE

EG (n = 15):

50 min/session, 2 sessions/week, 12 weeks

CG (n = 15): Non-exercise intervention VAS
Sudhakar, S. et al., 2017 [77] India RCT Female participants with primary dysmenorrhea 30 20.45 ± 3.42 MBE/CE

EG-1 (n = 15):

60s holding×5 reps×20s rest/exercise, 1 session/day, 3 days/week, 12 weeks

EG-2 (n = 15):

10s holding/exercise, 12 reps/set, 3 sets/day, 3 days/week, 12 weeks

VAS
Susan et al., 2018 [78] India RCT Adolescent girl (18–23 years) with primary dysmenorrhea 30 NA ME/SE

EG-1 (n = 15):

45 min/session, 3 sessions/week, 4 weeks

EG-2 (n = 15):

10 min/session, 3 sessions/week, 4 weeks

VAS
Temizkan and Budak, 2021 [79] Turkey Three-armed RCT Women (aged from 15–30 years) with primary dysmenorrhea 30 22.6 ± 1.99 AE/NE

EG (n = 15):

45 min/session, 3 sessions/week, 3 weeks

CG (n = 15): Non-exercise intervention MPQ
Tharani et al., 2018 [80] India RCT Girls aged 17–23 years with regular menstrual cycle and VAS scoring > 6 and DASS-21 scoring > 19 30 NA SE/AE

EG-1 (n = 15):

45 min/day, 3 days/week (alternate days), 8 weeks

EG-2 (n = 15):

45 min/day, 3 days/week (alternate days), 8 weeks

VAS
Yang and Kim, 2016 [81] Republic of Korea RCT Undergraduate nursing students with primary dysmenorrhea 36 21.06 ± 0.53 MBE/NE

EG (n = 18):

60 min/session, 1 session/week, 12 weeks.

CG (n = 18): Non-exercise intervention VAS
Yonglitthipagon et al., 2017 [11] Thailand RCT Non-athlete women with primary dysmenorrhea aged 18–22 years 34 19.89 ± 1.20 MBE/NE

EG (n = 17):

30 min/session, two sessions/week, 12 weeks

CG (n = 17): Non-exercise intervention VAS
Yosri, M.M. et al., 2022 [82] Egypt RCT Female participants (aged from 19–25 years) having normal menstrual cycles, who were diagnosed with primary dysmenorrhea. 120 19.85 ± 1.16 MBE/RE

EG-1 (n = 30):

4 yogic positions, 6 days/week, 8 weeks

EG-2 & EG-3 & EG-4 (n = 90):

4 yogic positions, 30 min of squatting exercise, 6 days/week, 8 weeks

VAS
ZAID et al., 2022 [83] Malaysia RCT

Female participants (aged from 18–29 years) with regular menstrual cycle and were diagnosed

with primary dysmenorrhea

24 22.58 ± 0.83 CE/NE

EG (n = 12):

10 reps/session, 10 min/session, 2 sessions/day, 5 days/weeks, 8weeks

CG (n = 12): Non-exercise intervention VAS

MBE Mind-body exercise, SE Stretching exercise, RE Resistance exercise, CE Core-strengthening exercise, AE Aerobic exercise, ME Multi-component exercise, NE Non-exercise intervention, AC Active control, EG Exercise group, CG Control group, VAS Visual analogue scale, NPRS Numerical pain rating scale, MPQ McGill pain questionnaire, RCT Randomized controlled trial, Sample number, NA Not Available, rep Repetition