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. 2024 Nov 16;24:610. doi: 10.1186/s12905-024-03453-w

Table 1.

Characteristics of included studies

Author (year) Country Study Design Participants N Mean age Comparison EG (time, frequency, duration) CG/EG (time, frequency, duration) Outcomes
Abbas et al., 2023 [36] Egypt RCT Post-acute COVID-19 women (aged from 18 to 25 years) suffering from primary dysmenorrhea 30 24.5 ± 2.60 ME/NE

EG (n = 15):

10 reps/exercise, 30 min/session, 2 sessions/day, 3 days/week, 4 weeks

CG (n = 15): Non-exercise intervention VAS
Abdelaziz et al., 2020 [37] Egypt RCT Female participants (aged from 14–20 years) had main complaints that were pain and cramping during menstruation 60 17.645 ± 0.93 MBE/AC

EG (n = 30):

30 min/session, 3 sessions/week, 12 weeks

CG (n = 30): Active control (Kinesiotaping) VAS
Agrawal and Ahmed, 2021 [38] Maharashtra RCT Female students between the age group 16–25 years who were unmarried with regular menstrual cycle, and had moderate to severe dysmenorrhea. 60 NA SE/CE

EG-1 (n = 30):

5 reps + holding/exercise, 1 session/day, 6 sessions/week, 8 weeks.

EG-2 (n = 30):

10 reps + holding/exercise, 1 session/day, 6 days/week, 8 weeks.

NPRS
Akbaş and Erdem, 2019 [39] Turkey RCT Female participants (aged 18–25 years) with primary dysmenorrhea (at least 4 on a 10 cm VAS) 37 21.15 ± 1.51 AE/NE

EG (n = 18):

50 min/session, 3 sessions/week, 4 weeks

CG (n = 19): Non-exercise intervention VAS
Aksu and Vefikuluçay, 2024 [40] Turkey RCT Female university students (18 years, with regular menstrual periods) were diagnosed with primary dysmenorrhea 60 20.05 ± 1.20 MBE/NE

EG (n = 30):

60 min/session, 2 sessions/week, 12 weeks

CG (n = 30): Non-exercise intervention VAS
Amreen et al., 2013 [41] India Three-armed RCT Female students (aged between 19–25 years) were screened for primary dysmenorrhea 24 21.08 ± 1.282 RE/AC

EG-1 & EG-2 (n = 16):

30 contraction/set, 3 sets/session, 3–4 sessions/week, 8 weeks

CG (n = 8): Active control (10 min hot pack) VAS
Arora et al., 2014 [42] Navi Mumbai RCT Young female participants (aged from 19–24 years) with primary dysmenorrhea 60 20.565 ± 1.516 AE/NE

EG (n = 30):

50 min/session, 3–5 sessions/week, 12 weeks

CG(n = 30): Non-exercise intervention VAS
Azima et al., 2015 [43] Iran RCT Students residing in dormitories of Shiraz University, who were majoring in nonmedical fields and had primary dysmenorrhea 68 20.91 ± 1.15 CE/NE

EG (n = 34):

10 times/session, 2 sessions/day, 5 days/week, 8 weeks

CG (n = 34): Non-exercise intervention VAS
Behbahani et al., 2016 [44] Iran RCT Single female below 25 years old, having primary dysmenorrhea with pain intensity of four and above based on VAS 80 20.25 ± 1.52 CE/AC

EG (n = 40):

8 weeks

CG (n = 40): Active control (Routine

treatment for dysmenorrhea)

MPQ
Berde, S.D. et al., 2019 [45] India RCT Female college students with primary dysmenorrhea 50 NA CE/AE EG-1 (n = 25): 4 days/week, 8 weeks EG-2 (n = 25): 4 days/week, 8 weeks VAS
Boztas Elverisli et al., 2022 [46] Turkey Five-armed RCT Female participants (aged from 18 to 30 years) with positive primary dysmenorrhea diagnosis 46 20.335 ± 1.64 ME/NE

EG (n = 23):

60 min/session, 2 sessions/week, 12 weeks

CG (n = 23): Non-exercise intervention VAS
Celik and Apay, 2021 [47] Turkey RCT

Female students who experienced dysmenorrhea according

to the VAS (scored 5 points or more)

124 20.17 ± 1.41 SE/NE

EG (n = 64):

30 min/session, 3–7 times/week, 8 weeks

CG (n = 60): Non-exercise intervention VAS
Chaudhuri et al., 2013 [48] India RCT School girls with recurrent, spasmodic menstrual cramps (primary dysmenorrhea) 128 (112) 14 ME/AC

EG (n = 53):

10–15 min/session, 2 sessions/day, 7 days/week, 12 weeks

CG (n = 75): Active control

(Hot water bottle)

VAS
Elbandrawy and Elhakk, 2021 [49] Egypt Three-armed RCT Female participants (aged from 18–25 years) with primary dysmenorrhea 105 22.39 ± 1.89 AE/CE/NE

EG-1 (n = 35):

45 min/session, 3 sessions/week, 8 weeks

EG-2 (n = 35):

5 reps + holding/exercise, 45 min/session, 3 sessions/week, 8 weeks

CG (n = 35): Non-exercise intervention VAS
Fallah and Mirfeizi, 2017 [50] Iran Four-armed RCT College students aged 15–18 years with primary dysmenorrhea 42 15.61 ± 0.94 SE/NE EG (n = 22): 20 min/session, 3 sessions/week, 2 times/day, 8 weeks CG (n = 20): Non-exercise intervention VAS
Huang et al., 2022 [51] China (Taiwan) RCT Females (aged from 18–40 years old), being afflicted with primary dysmenorrhea 30 21.05 ± 2.31 AE/NE

EG (n = 15):

30–35 min/session, 2 sessions/week, 10 weeks

CG (n = 15): Non-exercise intervention VAS
Ibrahim et al., 2023 [52] Saudi Arabia RCT Females (18–23 years) with primary dysmenorrhea 33 20.93 ± 1.25 SE/NE

EG (n = 22):

10 reps + holding/exercise, 30–45 min/session, 3 sessions/week, 4 weeks

CG (n = 11): Non-exercise intervention VAS
Jaibunnisha et al., 2017 [53] India RCT Female participants with regular menstrual cycle and diagnosed with primary dysmenorrhea 67 NA SE/NE

EG (n = 33):

10 min/session, 1 session/day, 6 days/week, 8 weeks

CG (n = 34): Non-exercise intervention NPRS
Kannan et al., 2019 [54] New Zealand RCT Women (18–43 years) with primary dysmenorrhea 55 NA AE/NE

EG (n = 35):

3 times/week, 28 weeks

CG (n = 35): Non-exercise intervention VAS
Kaur et al., 2014 [55] India Three-armed RCT Girls of age 19–25 years with primary dysmenorrhea were selected from lovely professional university and government college 105 NA SE/MBE/NE

EG-1 & EG-2 (n = 70):

4 days/week twice for 10 min, 8 weeks

CG (n = 35): Non-exercise intervention NPRS
Khare and Jain, 2015 [56] India RCT Primary dysmenorrhea cases (aged 15–17 years) 30 NA ME/NE

EG (n = 15):

30 min/session, 2 sessions/day, 3 times/week, 3 weeks

CG (n = 15): Non-exercise intervention VAS
Kirca and Celik, 2023 [57] Turkey RCT Female university students in the 3rd and 4th year (aged from 18 to 24 years) with primary dysmenorrhea, and have a VAS value of 6 and over 60 20.38 ± 0.48 MBE/NE

EG (n = 30):

60 min/session, one session/week, 12 weeks

CG (n = 30): Non-exercise intervention VAS
Kirmizigil and Demiralp, 2020 [58] Turkey RCT Women diagnosed with primary dysmenorrhea between the ages of 18 and 35 28 23 ± 1.92 ME/NE

EG (n = 14):

50 min/session, 3 times/week, 8 weeks.

CG (n = 14): Non-exercise intervention VAS
M.I. Ortiz et al., 2015 [59] Mexico RCT

Sedentary female patients with primary dysmenorrhea aged from 18–22 years

(pain intensity from 4 to 10 cm based on VAS)

160 20.25 ± 1.21 ME/NE

EG (n = 83):

50 min/session, 3 sessions/week, 12 weeks

CG (n = 77): Non-exercise intervention VAS
Mintu Merin et al., 2020 [60] India RCT Female participants (aged from 18–25 years) with any primary dysmenorrhea symptoms 50 21.86 ± 0.904 AE/CE

EG-1:

4 days/week, 8 weeks

EG-2:

10s holding/exercise, 12 times/set, 3 sets/day, 3 days/week, 8 weeks

VAS
Motahari-Tabari et al., 2017 [61] Iran RCT Students living in the university dormitory who had moderate to severe primary dysmenorrhea for more than 50% of menstrual cycles lasting for at least one day and affected their daily activities 122 21.45 ± 2.00 SE/AC

EG (n = 61):

15 min/session, 3 sessions/week, 8 weeks

CG (n = 61): Active control (Mefenamic acid treatment) VAS
Ozturk et al., 2023 [62] Turkey Three-armed RCT

University female students who scored menstrual pain 6 or higher on

the VAS

43 19.84 ± 1.51 SE/NE

EG (n = 22):

3 times/day on the first 3 days of the menstrual cycle, 8 weeks (two menstrual cycles).

CG (n = 19): Non-exercise intervention VAS
Pastor, S. et al., 2023 [63] India RCT Female college students (aged 18–25 years) with primary dysmenorrhea 30 19 ± 1.5 CE/AE EG-1 (n = 15): 5–12 repetitions/position, 40 min/session, 1 session/day, 4 days/week, 8 weeks EG-2 (n = 15): 5–12 repetitions/position, 40 min/session, 1 session/day, 4 days/week, 8 weeks NPRS
Patel et al., 2015 [64] India RCT Female participants (aged from 17 to 25 years) with regular menstrual cycles and experienced moderate to severe primary dysmenorrhea. 120 21.32 SE/NE EG (n = 60): 2 times/day, 3 days/week, 8 weeks CG (n = 60): Non-exercise intervention VAS
Qaisar and Abbas, 2023 [65] Pakistan RCT Female participants (aged 20–30 years) with primary dysmenorrhea 24 27.32 ± 2.08 CE/AC

EG (n = 12):

20s holding×10 reps/position, 5-mins rest/set, 20 min/session, 3 sessions/week, 6 weeks

CG (n = 12): Active control (Abdominal strengthening exercise with TENS) NPRS
Raja Laxmi V. et al., 2016 [66] India RCT Female participants (aged from 18–25 years) with primary dysmenorrhea 60 NA SE/CE EG-1 (n = 30): 10 min/session, 2 sessions/day, 4 days/week, 7 weeks EG-2 (n = 30): 20 min/session, 2 sessions/day, 4 days/week, 12 weeks VAS
Rakhshaee, 2011 [67] Iran RCT Female students with primary dysmenorrhea, 18–22 years old 92 20.67 MBE/NE EG (n = 50): 20 min/session, at least 14 days of the menstrual cycle (luteal phase), 8 weeks CG (n = 42): Non-exercise intervention VAS
Rashid et al., 2019 [68] Iran RCT Participants’ age ranges from 18 to 24 with mild to moderate dysmenorrhea during the last three periods according to the McGill pain scale (1 < score < = 6.6) 86 18.65 ± 0.64 AE/AC

EG (n = 43):

20–47 min/session, 3 sessions/week, 8 weeks

CG (n = 43): Active control (Two physical education classes once a week) VAS
Rostami et al., 2006 [69] Iran RCT Students had regular menstruation and severe primary dysmenorrhea 142 16.56 ± 1.12 ME/NE

EG (n = 97):

20 min/session, 2 sessions/day, 8 weeks

CG (n = 45): Non-exercise intervention VAS
S Saleh et al., 2016 [70] Egypt Three-armed RCT Participants experienced moderate to severe symptoms of dysmenorrhea 126 20.72 ± 1.15 SE/CE/NE

EG-1 (n = 44):

4 stretching exercises, 10 min/time, 3 times/day, 3 days/week, 8 weeks

EG-2 (n = 44):

4 core strengthening exercises, 20 min/time, 3 times/day, 4 days/week, 8 weeks

CG (n = 38): Non-exercise intervention VAS
Sakuma et al., 2012 [71] Japan RCT Healthy females (aged 20–64 years) 98 33.61 ± 12.02 MBE/NE

EG (n = 67):

one session/day, 7 days/week, 2 weeks

CG (n = 31): Non-exercise intervention VAS
Samy et al., 2019 [72] Egypt RCT Participants diagnosed with primary dysmenorrhea 98 21.47 ± 1.47 AE/NE

EG (n = 49):

60 min/session, 2 times/week, 8 weeks

CG (n = 49): Non-exercise intervention VAS
Shah et al., 2016 [73] India RCT Students from SPB Physiotherapy College 40 NA SE/NE

EG (n = 20):

4 days/week, 8 weeks

CG (n = 20): Non-exercise intervention VAS
Shahrjerdi et al., 2019 [74] Iran RCT Non-athletic, unmarried girls, aged 18–25 years, who suffered from moderate to severe primary dysmenorrhea 34 22.07 ± 0.98 CE/NE

EG (n = 17):

10 reps/exercise, 45–60 min/session, 3 sessions/week, 8 weeks.

CG (n = 17): Non-exercise intervention NPRS
Shirvani et al., 2017 [75] Iran RCT Female students living in the dormitory with moderate to severe primary dysmenorrhea 122 21.46 ± 2.05 SE/AC

EG (n = 61):

15 min/session, 3 sessions/week, 8 weeks

CG (n = 61): Active control (250 mg ginger capsules) VAS
Song and Kim, 2023 [76] Republic of Korea RCT Young female participants (aged from 19–39 years) with primary dysmenorrhea 30 32.6 ± 4.18 MBE/NE

EG (n = 15):

50 min/session, 2 sessions/week, 12 weeks

CG (n = 15): Non-exercise intervention VAS
Sudhakar, S. et al., 2017 [77] India RCT Female participants with primary dysmenorrhea 30 20.45 ± 3.42 MBE/CE

EG-1 (n = 15):

60s holding×5 reps×20s rest/exercise, 1 session/day, 3 days/week, 12 weeks

EG-2 (n = 15):

10s holding/exercise, 12 reps/set, 3 sets/day, 3 days/week, 12 weeks

VAS
Susan et al., 2018 [78] India RCT Adolescent girl (18–23 years) with primary dysmenorrhea 30 NA ME/SE

EG-1 (n = 15):

45 min/session, 3 sessions/week, 4 weeks

EG-2 (n = 15):

10 min/session, 3 sessions/week, 4 weeks

VAS
Temizkan and Budak, 2021 [79] Turkey Three-armed RCT Women (aged from 15–30 years) with primary dysmenorrhea 30 22.6 ± 1.99 AE/NE

EG (n = 15):

45 min/session, 3 sessions/week, 3 weeks

CG (n = 15): Non-exercise intervention MPQ
Tharani et al., 2018 [80] India RCT Girls aged 17–23 years with regular menstrual cycle and VAS scoring > 6 and DASS-21 scoring > 19 30 NA SE/AE

EG-1 (n = 15):

45 min/day, 3 days/week (alternate days), 8 weeks

EG-2 (n = 15):

45 min/day, 3 days/week (alternate days), 8 weeks

VAS
Yang and Kim, 2016 [81] Republic of Korea RCT Undergraduate nursing students with primary dysmenorrhea 36 21.06 ± 0.53 MBE/NE

EG (n = 18):

60 min/session, 1 session/week, 12 weeks.

CG (n = 18): Non-exercise intervention VAS
Yonglitthipagon et al., 2017 [11] Thailand RCT Non-athlete women with primary dysmenorrhea aged 18–22 years 34 19.89 ± 1.20 MBE/NE

EG (n = 17):

30 min/session, two sessions/week, 12 weeks

CG (n = 17): Non-exercise intervention VAS
Yosri, M.M. et al., 2022 [82] Egypt RCT Female participants (aged from 19–25 years) having normal menstrual cycles, who were diagnosed with primary dysmenorrhea. 120 19.85 ± 1.16 MBE/RE

EG-1 (n = 30):

4 yogic positions, 6 days/week, 8 weeks

EG-2 & EG-3 & EG-4 (n = 90):

4 yogic positions, 30 min of squatting exercise, 6 days/week, 8 weeks

VAS
ZAID et al., 2022 [83] Malaysia RCT

Female participants (aged from 18–29 years) with regular menstrual cycle and were diagnosed

with primary dysmenorrhea

24 22.58 ± 0.83 CE/NE

EG (n = 12):

10 reps/session, 10 min/session, 2 sessions/day, 5 days/weeks, 8weeks

CG (n = 12): Non-exercise intervention VAS

MBE Mind-body exercise, SE Stretching exercise, RE Resistance exercise, CE Core-strengthening exercise, AE Aerobic exercise, ME Multi-component exercise, NE Non-exercise intervention, AC Active control, EG Exercise group, CG Control group, VAS Visual analogue scale, NPRS Numerical pain rating scale, MPQ McGill pain questionnaire, RCT Randomized controlled trial, N Sample number, NA Not Available, rep Repetition