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. 2005 Jun 21;33(11):3550–3560. doi: 10.1093/nar/gki657

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© The Author 2005. Published by Oxford University Press. All rights reserved

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Kinetics of cytokine secretion in mice treated with CpG ODN fma1555. Female Balb/c mice (6–12 weeks of age, 3–6/group) were administered CpG ODN 1555 or CpG ODN fma1555 (100 μg/mouse) intraperitoneally and then euthanized 24, 72 or 120 h later. Shown in this graph are the number of cells secreting IL-6 and IL-12 (p40/p70) ex vivo, as determined by ELIspot for each time point.