Table 2. Distinct pathologic features that can differentiate primary and metastatic melanoma lesions.

*According to Billings et al. [9].

Presence of pathologic feature*	Primary melanoma*	Metastatic melanoma*
Junctional activity	44%	0%
Epidermal migration	38%	0%
Pigmentation	69%	20%
Extension of melanotic pigment into minor salivary glands	25%	0%